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| Observation on the curative effects of Ningmai Anshen Granules combined with Valsartan in the treatment of female climacteric hypertension patients with anxiety |
| Hits 1242 Download times 1113 Received:April 10, 2019 |
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| DOI
10.11656/j.issn.1672-1519.2019.09.11 |
| Key Words
Ningmai Anshen Granule;Valsartan;menopausal hypertension;anxious state |
| Author Name | Affiliation | E-mail | | QIAN Weidong | Department of Cardiology, Wujin Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Traditional Chinese Medicine, Changzhou 213161, China | | | SHI Yujing | Nanjing University of Traditional Chinese Medicine, Nanjing 210046, China | 810692519@qq.com |
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| Abstract
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| [Objective] To observe the effects of Ningmai Anshen Granules combined with Valsartan in the treatment of menopausal hypertension patients with anxiety.[Methods] The 78 cases of female climacteric hypertension with anxiety in our hospital were randomly divided into treatment group (39 cases) and control group (39 cases) by random number table method. The control group took the antihypertensive drug Valsartan 80 mg everyday orally,and the treatment group took a bag of Ningmai Anshen Granules once in the morning and the evening for a total of 8 weeks beside Valsartan. Blood pressure monitoring and HAMA scores were performed before and after the treatment in both groups,and hs-CRP and TNF-α were detected. The differences between the two groups before and after treatment were compared.[Results] After 8 weeks of treatment,the blood pressure drop in the treatment group was batter than that in the control group (P<0.05). HAMA scores improvement in the treatment group were better than that in the control group (P<0.05). Hs-CRP and TNF-α in the treatment group were batter than that in the control group (P<0.05).[Conclusion] Ningmai Anshen Granules can improve the curative effects and anxiety symptoms of female menopausal hypertension patients with anxiety state,which has certain advantages over western medicine alone. |
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