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| Qili Qiangxin Capsule for treatment of chronic heart failure:an overview of systematic reviews |
| Hits 1356 Download times 1137 Received:August 16, 2019 |
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| DOI
10.11656/j.issn.1672-1519.2019.11.15 |
| Key Words
Qili Qiangxin Capsule;chronic heart failure;overview of systematic review;AMSTAR2;GRADE |
| Author Name | Affiliation | E-mail | | PANG Wentai | Evidence-based Medicine Center, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | WANG Hucheng | Evidence-based Medicine Center, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | YANG Fengwen | Evidence-based Medicine Center, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | JIN Xinyao | Evidence-based Medicine Center, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | LI Nan | Evidence-based Medicine Center, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | WANG Keyi | Evidence-based Medicine Center, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | ZHENG Wenke | Evidence-based Medicine Center, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | zhengwk@tice.com.cn |
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| Abstract
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| [Objective] To evaluate the methodological quality and evidence level of outcomes about systematic review of Qili Qiangxin Capsule for chronic cardiac failure.[Methods] CNKI,Wanfang Data,SinoMed,PubMed,The Cochrane Library and Embase databases were researched to collect the systematic reviews of Qili Qiangxin Capsule for chronic heart failure. Date were retrieved from the inception of databases until April,2019. Two investigator screened literature independently and extracted data,and the methodological quality of systematic reviews were evaluated by AMSTAR2 scale,quality of evidence was graded by the GRADE system.[Results] A total of 15 systematic reviews were included. AMSTAR2 methodological quality evaluation results show that all systematic evaluation are low quality or very low quality. The results of GRADE evidence level evaluation showed that 15 systematic reviews included 12 outcomes,64 evidences. There were 1 high quality (1.6% of the total quantity),9 medium quality (14%),25 low quality (39%) and 29 very low quality (45.3%).[Conclusion] Qili Qiangxin Capsule in the treatment of chronic heart failure has good efficacy and safety,but the methodological quality and evidence level of systematic is low,and it is suggested that systematic review should be designed in a more rigorous and scientific way. |
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