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| Research progress on treatment of gout by xanthine oxidase inhibitor in traditional Chinese medicine |
| Hits 2312 Download times 969 Received:August 20, 2019 |
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| DOI
10.11656/j.issn.1672-1519.2019.12.23 |
| Key Words
gout;xanthine oxidase;traditional Chinese medicine;Chinese patent medicine |
| Author Name | Affiliation | E-mail | | WANG Aihua | Department of Rheumatology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of Traditional Chinese Medicine Prescription and Syndrome, Tianjin 300193, China | | | JIN Yue | Department of Rheumatology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of Traditional Chinese Medicine Prescription and Syndrome, Tianjin 300193, China | | | WU Yue | Department of Rheumatology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of Traditional Chinese Medicine Prescription and Syndrome, Tianjin 300193, China | | | CHENG Xuefei | Department of Rheumatology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of Traditional Chinese Medicine Prescription and Syndrome, Tianjin 300193, China | | | TIAN Qiuhong | Department of Rheumatology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of Traditional Chinese Medicine Prescription and Syndrome, Tianjin 300193, China | | | XIE Qing | Department of Rheumatology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of Traditional Chinese Medicine Prescription and Syndrome, Tianjin 300193, China | | | LIU Wei | Department of Rheumatology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of Traditional Chinese Medicine Prescription and Syndrome, Tianjin 300193, China | fengshiliuwei@163.com |
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| Abstract
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| Xanthine oxidase is an important metabolic enzyme of purine,which can catalyze the transformation of hypoxanthine into xanthine,and then catalyze xanthine to produce uric acid. High levels of uric acid in the body can lead to hyperuricemia,which can lead to the onset of gout. Xanthine oxidase inhibitors can reduce the activity of XOD. At present,most western drugs such as allopurinol and febuxostat have great side effects. In this paper,the extraction of xanthine oxidase inhibitors from traditional Chinese medicine and Chinese patent medicine for the treatment of hyperuricemia and gout were reviewed in detail. It provides useful reference for related research. |
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