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| Effect of tonifying lung and kidney therapy on IFN-γ,IL-4 and IL-13 in child patients with allergic asthma |
| Hits 1242 Download times 785 Received:November 12, 2019 |
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| DOI
10.11656/j.issn.1672-1519.2020.02.17 |
| Key Words
allergic asthma;tonifying lung and kidney method;IFN-γ;IL-4;IL-13 |
| Author Name | Affiliation | E-mail | | CHEN Hong | First Department of Pediatrics, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin 150040, China | | | ZHANG Wei | First Department of Pediatrics, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin 150040, China | | | SU Yuming | First Department of Pediatrics, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin 150040, China | | | LI Quan | Heilongjiang University of Chinese Medicine, Harbin 150040, China | | | CHEN Qun | Department of Examination, Harbin Acheng District People's Hospital, Harbin 150300, China | | | SONG Qiannan | Heilongjiang University of Chinese Medicine, Harbin 150040, China | | | WANG Xinyu | Heilongjiang University of Chinese Medicine, Harbin 150040, China | | | LI Meixu | Heilongjiang University of Chinese Medicine, Harbin 150040, China | | | ZHANG Jing | Heilongjiang University of Chinese Medicine, Harbin 150040, China | | | CHI Yuan | Heilongjiang University of Chinese Medicine, Harbin 150040, China | | | JIANG Wei | First Department of Pediatrics, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin 150040, China | chenrongsheng1977@163.com |
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| Abstract
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| [Objective] To investigate the effect of tonifying lung and kidney therapy on IFN-γ,IL-4 and IL-13 in patients with allergic asthma.[Methods] The 108 child patients with allergic asthma admitted to our hospital from June 2017 to July 2018 were divided into observation group and control group according to random number table method,54 cases in each group. The control group was treated with routine western medicine,while the observation group was treated with tonifying lung and kidney method on the basis of the routine western medicine. The expression of IFN-γ,IL-4 and IL-13 were compared between the two groups.[Results] The total effective rate was 94.44% in the observation group and 88.89% in the control group,with no significant difference between the two groups(P>0.05). After treatment,the scores of chest tightness,cough,heart rate and pulse pressure difference in the observation group were higher than those in the control group (P<0.05). After treatment,the levels of IL-4 (1.72±0.35) ng/mL,IL-13 (2.33±0.54) ng/mL in the observation group were lower than those in the control group,and the levels of IFN-γ (18.25±1.67) ng/mL in the observation group were higher than those in the control group (P<0.05).[Conclusion] The therapy of tonifying lung and kidney can effectively reduce the levels of IFN-γ,IL-4 and IL-13 in patients with allergic asthma,and correct the imbalance of Th1/Th2 cytokines. The clinical effect is good and worthy of recommendation. |
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