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Signal pathways of precancerous lesions of gastric cancer and the related research progress of traditional Chinese medicine treatment
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DOI   10.11656/j.issn.1672-1519.2020.02.24
Key Words   precancerous lesion of gastric cancer;signal pathway;traditional Chinese medicine
Author NameAffiliationE-mail
ZHANG Manling Hubei University of Chinese Medicine, Wuhan 430065, China  
SHI Zhaohong Wuhan Hospital of Traditional Chinese Medicine and Western Medicine, Affiliated to Hubei University of Chinese Medicine, Wuhan 430022, China zhaohshi@126.com 
LIU Yun Hubei University of Chinese Medicine, Wuhan 430065, China  
ZHAO Wenyingzi Hubei University of Chinese Medicine, Wuhan 430065, China  
Abstract
    The incidence and mortality of gastric cancer among all kinds of cancers are both high in China. The precancerous lesion of gastric cancer (PLGC) plays an important role in the process of gastric carcinogenesis. Earlier diagnosis and treatment of PLGC can reduce the risk of developing into gastric cancer. At present,the therapy methods of PLGC contains anti-Hp treatment,supplement of kinds of vitamins,folic acid,non-steroidal drugs,and intensive follow-up. However,the curative effects of above strategies are still controversial. The traditional Chinese medicine (TCM) has its unique feature. It has been proved by many researches that the TCM has significant effect in PLGC treatment,but the mechanism is not completely clear. This article summarizes the dominating signal pathways of precancerous lesions of gastric cancer and the related research progress of TCM.

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