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Study on dampness-heat syndrome of jin ju (non-ischemic gangrene of diabetic foot) based on glucose and lipid metabolism
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DOI   10.11656/j.issn.1672-1519.2020.03.14
Key Words   jin ju (non-ischemic gangrene of diabetic foot);dampness heat and excessive toxin syndrome;glucose and lipid metabolism
Author NameAffiliationE-mail
LI Liangliang Department of Vascular Anomalies, Shanghai University of Traditional Chinese Medicine, Shanghai TCM-Integrated Hospital, Shanghai 200082, China  
WANG Weiling Department of Vascular Anomalies, Shanghai University of Traditional Chinese Medicine, Shanghai TCM-Integrated Hospital, Shanghai 200082, China  
ZHAO Cheng Department of Vascular Anomalies, Shanghai University of Traditional Chinese Medicine, Shanghai TCM-Integrated Hospital, Shanghai 200082, China
Clinical Laboratory, Shanghai TCM-Integrated Institute of Vascular Anomalies, Shanghai 200082, China 
Chengzhao_79@163.com 
Abstract
    [Objective] Study on glucose and lipid metabolism indexes of dampness-heat syndrome of jin ju (non-ischemic gangrene) in diabetic foot by modern testing techniques.[Methods] A total of 136 patients with jin ju (diabetic foot non-ischemic gangrene) were collected and compared for different syndrome types.[Results] The levels of FBG,HbA1c,2 hPBG,AGEs,ALB,TC,HDL-C in patients with dampness-heat syndrome were different from those in other syndromes of jin ju (non-ischemic gangrene) (P<0.05). And the levels of CRP and sVCAM-1 in patients with dampness-heat syndrome were significantly different from those in other syndromes of jin ju (non-ischemic gangrene) (P<0.01).[Conclusion] The cause of the formation of jin ju (non-ischemic gangrene) dampness-heat toxin in diabetic foot is related to hyperglycemia and persistent inflammatory response caused by disorders of glucose and lipid metabolism in low-nutrition conditions.

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