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Comparative study on TCM syndrome evaluation scale of phlegm and blood stasis syndrome in coronary heart disease with stable angina pectoris
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DOI   10.11656/j.issn.1672-1519.2020.06.14
Key Words   coronary heart disease with stable angina pectoris;phlegm and blood stasis syndrome;qi and yin deficiency syndrome;TCM syndrome evaluation scale
Author NameAffiliationE-mail
ZHAO Jia Tianjin Chest Hospital, Tianjin 300222, China  
WANG Xu Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
GAO Shuming Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
LI Lin Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
GAO Shan Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
LI Chunjie Tianjin Chest Hospital, Tianjin 300222, China ykwn@sina.com 
YU Chunquan Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China ycq-4@163.com 
Abstract
    [Objective] To explore the similarities and differences of traditional Chinese medicine (TCM) syndrome evaluation scale between patients with and phlegm and blood stasis syndrome,qi and yin deficiency syndrome in coronary heart disease (CHD) stable angina pectoris and healthy people.[Methods] Through a multi-center,small sample and refined clinical study,124 subjects in 7 clinical units were included in the study and 7 cases were lost,finally 117 subjects were included,including 38 cases of phlegm and blood stasis syndrome patients with conventional Western treatment and traditional Chinese medicine Danlou Tablets,39 cases of qi and yin deficiency syndrome patients with Western treatment and Chinese medicine Tongmai Yangxin Pills,and 40 cases of healthy people without intervention. The scores of TCM syndrome evaluation scale of coronary heart disease with phlegm and blood stasis syndrome were evaluated at different time points in different groups and groups. Coronary heart disease patients were detected at 0th,4th,8th and 12th week,respectively,and at the 0th week,the level of healthy people was detected.[Results] 1)At the 4th,8th and 12th week of CHD with phlegm and blood stasis syndrome,the scores of each symptom and sublingual vein bruise were significantly lower than those of 0th week (P<0.05 or P<0.01). 2) At the 4th,8th and 12th week of CHD patients with qi and yin deficiency syndrome,the score of each symptom decreased compared with 0th week (P<0.05 or P<0.01). 3) Compared with healthy people,there were significant differences in scores among patients with CHD of phlegm and blood stasis syndrome (P<0.01). Patients with CHD of qi and yin deficiency syndrome were significant differences in scores of each symptom and dark purple tongue (P<0.05 or P<0.01). CHD in two groups at different time points,some indicators and tongue existed different degrees of difference. 4) Patients with CHD,phlegm and blood stasis syndrome 0th,8th weeks,weight,mouth sticky,greasy moss,slippery pulse,tongue ecchymosis clustered together,while pulse string,dark purple tongue,pulse astringent,purple lips,dark complexion clustered together. CHD qi and yin deficiency syndrome patients at 0th,8th weeks,chest tightness,chest pain,weight,mouth sticky,lips purple,dull complexion,tongue stasis,dark purple tongue,astringent pulse clustered together.[Conclusion] Patients with CHD phlegm and blood stasis syndrome,qi and yin deficiency syndrome showed improvement in the TCM syndrome evaluation scale indicators after treatment,and two syndromes showed different presentation. It suggested CHD phlegm and blood stasis syndrome TCM syndrome evaluation scale can provide a reference for clinical diagnosis and treatment of CHD patients with stable angina pectoris of phlegm and blood stasis syndrome.

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