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| Distribution of traditional Chinese medicine syndrome types and characteristics of renal function injury in chronic heart failure patients with cardiorenal syndrome |
| Hits 1082 Download times 722 Received:April 30, 2020 |
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| DOI
10.11656/j.issn.1672-1519.2020.08.10 |
| Key Words
chronic heart failure;cardiorenal syndrome;traditional Chinese medicine syndrome type;glomerular filtration rate;NYHA grade |
| Author Name | Affiliation | | ZHANG Yibao | Medical ICU, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China |
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| Abstract
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| [Objective] To investigate the distribution of traditional Chinese medicine(TCM) syndromes in patients with cardiorenal syndrome (CRS) and the changes of renal function with different TCM syndromes.[Methods] The 91 patients with CHF and CRS in our clinic or ward were surveyed and required to determine renal function(Cr,BUN,UA).Estimated glomerular filtration rate(eGFR) was calculated according to MDRD formula. The changes of renal function in different groups divided by TCM syndromes were analyzed.[Results] The number of hart-kidney yang deficiency was the largest(35.16%),and deficiency of both qi and yin was the least(6.59%). GFR of hart-kidney yang deficiency group and edema due to yang deficienlc group was lower than the other groups (P<0.05). Compared with NYHA grade Ⅱ,GFR of NYHA grade Ⅲ and Ⅳ was significantcy lower (P<0.01). After the adjustment for age factors,the differences still existed. NYHA grading entered the final logistic equation:logitP=-1.946+2.248X1+1.841X2. CHF patients with NYHA grade increase is an independent risk factor for significant renal impairment.[Conclusion] Hart-kidney yang deficiency syndrome and edema due to yang deficiency syndrome were the severe late stages for the CHF,of which GFR decreased compared with other syndromes. CHF patients with NYHA grade increase is an independent risk factor for significant renal impairment. |
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