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| To analyze rules of Professor GAO Ying in treating relapses and disability in multiple sclerosis based on complex network |
| Hits 1004 Download times 708 Received:April 22, 2020 |
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| DOI
10.11656/j.issn.1672-1519.2020.11.18 |
| Key Words
multiple sclerosis;relapse;disability;traditional Chinese medicine;complex network |
| Author Name | Affiliation | E-mail | | XIE Yao | Dongzhimen Hospital, Beijing University of Chinese Medcine, Beijing 100007, China | | | SUGIMOTO KAZUO | Dongzhimen Hospital, Beijing University of Chinese Medcine, Beijing 100007, China | | | YAN Dong | Dongzhimen Hospital, Beijing University of Chinese Medcine, Beijing 100007, China | | | GAO Ying | Dongzhimen Hospital, Beijing University of Chinese Medcine, Beijing 100007, China | gaoying973@163.com |
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| Abstract
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| [Objective] To analyze rules and ideas of traditional Chinese medicine in treating relapses and disability in relapsing-remitting multiple sclerosis.[Methods] After selecting effective prescriptions for relapses and disability,python and Gephi were used to perform the complex network,then cluster analysis was performed for the core herbs.[Results] The 152 effective prescriptions were included. In the complex network analysis,162 nodes and 3 883 edges were found,and average degree was 47.94. The core nodes were Radix Rehmanniae,Radix Curcumae,dogwood,Poria Cocos,etc. In the matrix list,3 884 herb pairs were generated,among which the highest weight was Rehmannia and dogwood.[Conclusion] Core herbs were Rehmanniae,Radix Curcumae,dogwood,Poria Cocos,siegesbeckiae,Rhizoma Anemarrhenae,Fructus Ligustri Lucidi,Yam Rhizome,clematis root,Radix Scutellariae,etc. The most common used herb pairs were Rehmanniae and dogwood,Rehmanniae and Poria,dogwood and Poria. The main treatment was to reinforce liver and kidney,combining clear heat and wet,detoxification and dredging collaterals. And the treatment was dynamic and flexible. |
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