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| Effect of Zhongtong Cataplasms on rats with closed soft tissue injury |
| Hits 866 Download times 676 Received:July 15, 2020 |
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| DOI
10.11656/j.issn.1672-1519.2020.12.21 |
| Key Words
Zhongtong Cataplasms;closed soft tissue injury;effect |
| Author Name | Affiliation | | HU Huanfu | Yueyang Vocational Technical College, Key Laboratory of Elderly Health Conservation, Yueyang 414000, China | | RUAN Bin | Yueyang Vocational Technical College, Key Laboratory of Elderly Health Conservation, Yueyang 414000, China | | ZOU Jin | Yueyang Vocational Technical College, Key Laboratory of Elderly Health Conservation, Yueyang 414000, China | | LI Xiping | Yueyang Vocational Technical College, Key Laboratory of Elderly Health Conservation, Yueyang 414000, China |
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| Abstract
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| [Objective] To observe the effect of Zhongtong Cataplasms on rats with closed soft tissue injury and provide experimental basis for its clinical medication.[Methods] The SD rats were randomly divided into 6 groups,which were administered after modeling,and the symptom index score and histomorphology of the injury site were examined,and the perimeter of the injury mark and the content of prostaglandin E2 (PGE2) in the tissue were measured.[Results] Compared with blank and model control groups,the middle and high dose group of Zhongtong Cataplasms can significantly reduce the circumference of the swollen calf and damage symptom index in rats with closed soft tissue injury. The high dose group can significantly reduce the content of PGE2 and improve the histomorphology (P<0.05).[Conclusion] Zhongtong Cataplasms has a significant effect on rats with closed soft tissue injury. |
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