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| Research review of integrated traditional Chinese and Western medicine for hepatitis B virus associated glomerulonephritis |
| Hits 1511 Download times 961 Received:August 10, 2020 |
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| DOI
10.11656/j.issn.1672-1519.2021.01.27 |
| Key Words
hepatitis B virus associated glomerulonephritis;renal fibrosis;integrated traditional Chinese and Western medicine |
| Author Name | Affiliation | | WANG Yaoguang | First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China | | WAN Yingying | First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China |
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| Abstract
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| Hepatitis B virus associated glomerulonephritis is a disease caused by the deposition of immune complexes in the kidneys after infection with hepatitis B virus. It is one of the common secondary glomerular diseases in China. It is more common in children and has a better prognosis. Partial development to advanced stages can cause renal interstitial fibrosis. At present,there is no reliable animal model and it is highly contagious,which leads to some difficulties in the research of hepatitis B virus associated glomerulonephritis. Molecular biology mainly focuses on cell transfection,and research suggests that hepatitis B virus X protein (HBx) is related to apoptosis of renal tubular epithelial cells. Current research bottlenecks are the lack of experimental research,the lack of a unified clinical treatment plan,and the lack of large-scale,multi-center research. The most effective way to prevent hepatitis B virus infection is to inoculate hepatitis B vaccine. At present,the treatment of hepatitis B virus associated glomerulonephritis with integrated traditional Chinese and Western medicine has achieved certain clinical effects. Traditional Chinese medicine has achieved certain clinical effects in treating hepatitis B virus associated glomerulonephritis and preventing and treating renal fibrosis from the aspects of syndrome differentiation,treatment by stages,and special prescriptions of traditional Chinese medicine. This article will discuss hepatitis B virus associated glomerulonephritis from four parts:research bottleneck,experimental research progress,research direction and prospect,in order to provide reference for clinical treatment of hepatitis B virus associated glomerulonephritis. |
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