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Theoretical discussion on the treatment of cerebral small vessel disease by using the assistant medications pair of “Radix Polygoni Multiflori-Polygonum cuspidatum”
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DOI   10.11656/j.issn.1672-1519.2021.05.05
Key Words   cerebral small vessel disease;Radix Polygoni Multiflori-Polygonum cuspidatum;assistant medications pair;theroy of traditional Chinese medicine;pharmacological research
Author NameAffiliationE-mail
LI Xin Affiliated Hospital ofShandong University ofTraditional Chinese Medicine, Jinan 250014, China  
ZHANG Jie Shandong University of Traditional Chinese Medicine, Jinan 250355, China  
LIU Wei Shandong University of Traditional Chinese Medicine, Jinan 250355, China  
WANG Dongxian Shandong University of Traditional Chinese Medicine, Jinan 250355, China  
WANG Zhonglin Shandong University of Traditional Chinese Medicine, Jinan 250355, China  
HAN Xiaohui Shandong University of Traditional Chinese Medicine, Jinan 250355, China  
WANG Xinlu Shandong University of Traditional Chinese Medicine, Jinan 250355, China siemensxzy@qq.com。 
Abstract
    Turbidity of blood is an important pathological factor of cerebral small vessel disease. Treating cerebral small vessel diseasefrom turbid blood hurting marrow can provide new ideas for clinical diagnosis and treatment of cerebral small vessel disease. "Radix Polygoni Multiflori-Polygonum cuspidatum" is an important component of Huazhuo Xingxue Decoction,which has the function of dispelling turbidityand benefiting marrow. This article mainly discusses the treatment of cerebral small vessel disease with the assistant medications pair of"Radix Polygoni Multiflori-Polygonum cuspidatum" from four aspects:etiology and pathogenesis,treatment principle,compatibility significance andrelated pharmacological research.

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