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| Clinical study of Huoluo Xiaoling Dan in treating saphenous nerve injury after endovenous laser treatment in varicose veins |
| Hits 1072 Download times 626 Received:January 15, 2021 |
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| DOI
10.11656/j.issn.1672-1519.2021.05.11 |
| Key Words
Huoluo Xiaoling Dan;lower extremity varicose veins;endovenous laser treatment;saphenous nerve injury;36-item health survey short-form |
| Author Name | Affiliation | E-mail | | CHEN Zhibin | Department of Vascular Surgery, Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China | | | HUANG Rong | Department of Vascular Surgery, Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China | | | HUANG Yi | Department of Vascular Surgery, Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China | | | ZENG Guang | Department of Vascular Surgery, Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China | | | JIN Yongzhi | Department of Vascular Surgery, Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China | | | LI Mengfan | Department of Vascular Surgery, Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China | 18601613808@163.com。 |
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| Abstract
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| [Objective] To explore the application value of Huoluo Xiaoling Dan on saphenous nerve injury after endovenous laser treatment (EVLT).[Methods] From January 2018 to October 2019,60 patients with varicose veins of the great saphenous vein of lower limbs were selected as the research objects. All patients had pain,numbness and other symptoms of saphenous nerve injury,and were divided into two groups with 30 cases in each group by random number table method. The observation group was treated with horse chestnut seed extract tablets combined with Huoluo Xiaoling Dan,while the control group was treated with horse chestnut seed extract tablets combined with mecobalamine tablets. All subjects stopped using horse chestnut seed extract tablets after continuous treatment for one month,and the other drugs were used for another two months,with a course of treatment of three months. The clinical efficacy and safety of two groups were compared. Before and after treatment,the subjective pain degree of the subjects was quantitatively evaluated by the "subjective pain rating method",the saphenous nerve conduction velocity of the affected limb was measured,and the quality of life was evaluated[36-item health survey short-form (SF-36)].[Results] The total effective rate of the observation group[93.33% (28/30)] was significantly higher than that of the control group[60.00% (18/30)] (P<0.05). After treatment,there was no significant difference in the incidence of subjective pain between two groups (P>0.05). With the prolongation of treatment time,the conduction velocity of saphenous nerve increased gradually in both groups (P<0.05). Moreover,the saphenous nerve conduction velocity of the affected limb in the observation group was significantly higher than that in the control group at the same time (P<0.05). The scores of SF-36 in two groups increased gradually with the prolongation of treatment time (P<0.05),but the scores of SF-36 in the observation group were significantly higher than those in the control group during the same period (P<0.05). No obvious adverse events occurred in both groups.[Conclusion] The application of Huoluo Xiaoling Dan can effectively promote the recovery of damaged saphenous nerve in patients after EVLT and improve their life quality,with high safety. |
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