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| Effect of Yishen Nuangong Decoction combined with acupuncture on pregnancy outcome and sex hormone level in patients with multiple IVF-ET |
| Hits 897 Download times 644 Received:April 06, 2021 |
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| DOI
10.11656/j.issn.1672-1519.2021.06.17 |
| Key Words
Yishen Nuangong Decoction;acupuncture;in vitro fertilization-embryo transfer;pregnancy;sex hormone |
| Author Name | Affiliation | E-mail | | ZHU Lei | Department of Gynecology, Traditional Chinese Medicine Hospital of Kunshan, Kunshan 215300, China | | | PENG Huiping | Department of Gynecology, Traditional Chinese Medicine Hospital of Kunshan, Kunshan 215300, China | | | CHEN Yi | Department of Gynecology, Traditional Chinese Medicine Hospital of Kunshan, Kunshan 215300, China | | | ZHANG Jinwei | Department of Gynecology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi 214023, China | 15961882137@163.com |
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| Abstract
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| [Objective] To investigate the therapeutic effect of Yishen Nuangong Decoction combined with acupuncture on multiple in vitro fertilization and embryo transfer (IVF-ET) patients and its influence on pregnancy outcome and sex hormone level.[Methods] The 150 patients with IVF-ET who met the criteria of experimental cases were divided into observation group and control group by random number table method,75 cases in each group. The control group was treated with long-term routine combined with acupuncture and moxibustion treatment of corpus luteum in vitro,while the observation group was treated with modified Yishen Nuangong Decoction combined with acupuncture and moxibustion to observe its effect on clinical efficacy,pregnancy rate and sex hormone level.[Results] There was no significant difference in the number of ova taken,fertilization rate and cleavage rate of fertilized ova between two groups (P>0.05). The rate of high-quality ova and high-quality embryos in the observation group were significantly higher than those in the control group (P<0.05),and the biochemical pregnancy rate and clinical pregnancy rate in the observation group were significantly higher than those in the control group (P<0.05). The levels of follicle-forming hormone (FSH),luteinizing hormone (LH),estradiol (E2) and progesterone (P) in the observation group were significantly higher than those in the control group (P<0.05). There was no significant difference in TCM syndrome scores between two groups before treatment (P>0.05). After treatment,the traditional Chinese medicine syndrome scores of the two groups decreased significantly (P<0.05),and the observation group was significantly lower than the control group (P<0.05). The curative effect of TCM syndrome (88.00%) was significantly higher than that of the control group (69.33%) with significant difference (P<0.05).[Conclusion] Yishen Nuangong decoction combined with acupuncture has a good effect in treating multiple IVF-ET,whether it is caused by the combined effect needs further research to confirm. |
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