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| Observation on curative effects of conventional treatment combined with Qishen Yiqi Dropping Pill in treating chronic heart failure of coronary heart disease |
| Hits 785 Download times 747 Received:March 26, 2021 |
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| DOI
10.11656/j.issn.1672-1519.2021.07.11 |
| Key Words
Qishen Yiqi Dropping Pill;coronary heart disease;heart failure;cardiac function |
| Author Name | Affiliation | E-mail | | ZHANG Kaixuan | Department of Cardiovascular, Baoding First Central Hospital, Baoding 071000, China | | | GENG Wei | Department of Cardiovascular, Baoding First Central Hospital, Baoding 071000, China | docgwei@163.com | | TIAN Xiang | Department of Cardiovascular, Baoding First Central Hospital, Baoding 071000, China | | | ZHANG Qi | Department of Cardiovascular, Baoding First Central Hospital, Baoding 071000, China | | | WANG Xiao | Department of Cardiovascular, Baoding First Central Hospital, Baoding 071000, China | | | SONG Weili | Department of Cardiovascular, Baoding First Central Hospital, Baoding 071000, China | |
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| Abstract
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| [Objective] To observe the clinical effects of QishenYiqi Dropping Pill in treating chronic heart failure of coronary heart disease.[Methods] A total of 300 patients with chronic heart failure of coronary heart disease in Baoding First Central Hospital from September 2017 to December 2018 were enrolled. The patients were randomly divided into control group (n=150,routine treatment) and experimental group (n=150,routine treatment combined with Qishen Yiqi Dripping Pills). The left ventricular ejection fraction (LVEF),left ventricular end diastolic diameter (LVEDd),N-terminal pro brain natriuretic peptide (NT-proBNP) level and the occurrence of adverse cardiovascular events were observed before treatment,6 months after treatment and 12 months after treatment.[Results] Finally,291 patients were included in the study,including 147 cases in the experimental group and 144 cases in the control group. The levels of LVEF,LVEDd and NT-proBNP in the two groups were compared at 6 months and 12 months after treatment,the LVEF,LVEDd and NT-proBNP in the experimental group and the control group were improved compared with those before treatment,and the difference was statistically significant (P<0.05). The improvement degree of LVEF,LVEDd and NT-proBNP in the experimental group was better than that in the control group (P<0.05). After 12 months' follow-up,the readmission rate of the experimental group due to cardiovascular disease (25.9%) was significantly lower than that of the control group (42.4%),with a statistically significant difference (P<0.05). And the total incidence of adverse cardiovascular events (29.3%) was significantly lower than that of the control group (47.2%),with a statistically significant difference (P<0.05).[Conclusion] Conventional Western medicine combined with Qishen Yiqi Dripping Pill can improve the heart function of patients with coronary heart disease and chronic heart failure, and reduce the rate of rehospitalization due to cardiovascular disease and the overall incidence of adverse heart failure events. It is worthy of clinical application. |
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