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Clinical observation of Chaiqi decoction in treating metabolic syndrome of liver stagnation and spleen deficiency
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DOI   10.11656/j.issn.1672-1519.2021.09.10
Key Words   Chaiqi Decoction;metabolic syndrome;insulin resistance;glucose and lipid metabolism
Author NameAffiliationE-mail
WANG Ying Department of Endocrinology, Dongfang Hospital Beijing University of Chinese Medicine, Beijing 100078, China  
ZHANG Liping Graduate School of Beijing University of Chinese Medicine, Beijing 100029, China lpzhang2005@126.com 
SUN Hongfeng Department of Endocrinology, Dongfang Hospital Beijing University of Chinese Medicine, Beijing 100078, China  
LIU Jing Department of Endocrinology, Dongfang Hospital Beijing University of Chinese Medicine, Beijing 100078, China  
Abstract
    [Objective] To observe the clinical efficacy of Chaiqi Decoction in treating patients with metabolic syndrome of liver depression and spleen deficiency.[Methods] Using a random number table method,80 patients with metabolic syndrome of liver depression and spleen deficiency were divided into two groups. The control group received 40 patients with basic treatment(control diet and appropriate exercise);the treatment group received 40 patients with basic treatment and Chaiqi Decoction. After 3 months of treatment,the changes in blood pressure,BMI,FPG,FINS,HOMA-IR,and blood lipids of the two groups were observed,and the efficacy of traditional Chinese medicine(TCM) syndromes was evaluated.[Results] The blood pressure,BMI,FPG,FINS,HOMA-IR,and blood lipids of the treatment group were improved compared with those before treatment(P<0.05);compared with the control group,systolic blood pressure,FPG,FINS,HOMA-IR,TC,LDL-C improved significantly(P<0.05);comparing the efficacy of TCM syndromes between the two groups,the total effective rate of the treatment group was significantly higher than that of the control group(P<0.05).[Conclusion] Chaiqi Decoction was effective in treating metabolic syndrome of liver depression and spleen deficiency,which can improve insulin resistance and regulate glucose and lipid metabolism.

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