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| Study on characteristics of TCM syndrome in uremia patients with peritoneal dialysis complicated with vascular calcification |
| Hits 779 Download times 527 Received:March 30, 2021 |
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| DOI
10.11656/j.issn.1672-1519.2021.09.12 |
| Key Words
peritoneal dialysis;vascular calcification;syndrome characteristics |
| Author Name | Affiliation | E-mail | | JIANG Chen | Department of Nephrology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300384, China | | | SONG Yu | Department of Nephrology, Heze Traditional Chinese Medicine Hospital, Heze 274000, China | | | LYU Yang | Department of Emergency, Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China | | | YANG Hongtao | Department of Nephrology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300384, China | tjtcmht@126.com |
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| Abstract
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| [Objective] To investigate the incidence and the characteristics of traditional Chinese medicine (TCM) syndromes in vascular calcification patients with peritoneal dialysis due to uremia,in order to provide evidence for the TCM treatment for peritoneal dialysis with vascular calcification.[Methods] The incidence of vascular calcification in 421 peritoneal dialysis patients were retrospectively analyzed. By collecting information on gender,age,clinical elements,calcification and TCM syndromes of 125 patients with peritoneal dialysis and vascular calcification. Diagnosis and classification of syndromes,summarize and analyze the laws of syndromes,and further explore the correlation between gender,age,clinical elements and the distribution of syndromes.[Results] The incidence of vascular calcification in the dialysis center was 29.7%. Among them,patients with simple heart valve calcification were the majority (80.0%). The analysis of the law of TCM syndromes showed that the distribution law of the deficiency of the spleen and kidney was as follows:spleen-kidney yang deficiency syndrome (48.0%),followed by qi-yin deficiency syndrome (20.0%),spleen-kidney qi deficiency syndrome (17.6%),liver-kidney yin deficiency syndrome (8.0%),yin-yang deficiency syndrome (6.4%);The main standard positivity were dampness-heat syndrome (49.5%),followed by dampness and turbidity syndrome (26.6%),blood stasis syndrome (15.6%),and moisture and gas syndrome (7.3%). In addition,there were statistical differences in the distribution of the composition ratio of the original deficiency syndrome and standard positivity of patients of different ages and dialysis ages (the original deficiency syndrome P<0.01;the standard empirical syndrome P<0.05). The proportion of spleen-kidney yang deficiency syndrome increased with the older age and the older dialysis age (P<0.01). Gender had no obvious influence on the distribution of TCM syndromes. The serum creatinine level had a significant effect on the identification of this deficiency syndrome,and the patients with higher serum creatinine were more likely to have spleen-kidney yang deficiency syndrome (P<0.01). The level of serum potassium affected the differentiation of the standard positivity syndrome (P<0.01),and the levels of hemoglobin and plasma albumin significantly affected the distribution of both the standard positivity and the deficiency syndrome of spleen-kidney yang,which was more obvious in patients with poor nutritional status.[Conclusion] In uremic patients with peritoneal dialysis complicated with vascular calcification,the main syndrome was spleen-kidney yang deficiency and damp-heat syndrome. Age and dialysis age are factors which affects the distribution of TCM syndromes. The influence of laboratory examination on syndrome typing should also be considered in clinical syndrome differentiation. The nutritional status of patients has important reference for clinical syndrome differentiation. |
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