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Preliminary study on the guiding significance of turbid blood-turbid brain-brain toxicity theory in the prevention and treatment against Alzheimer's disease
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DOI   10.11656/j.issn.1672-1519.2021.09.14
Key Words   turbid blood;turbid brain;brain toxicity;Alzheimer's disease;Yishen Huazhuo method
Author NameAffiliationE-mail
ZHAO Guanhua Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
SUN Weiming Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China  
WANG Kai Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China  
CUI Yuanwu Bao'an Authentic Traditional Chinese Medicine Therapy Hospital, Shenzhen 518100, China pxcyw@126.com 
Abstract
    The etiology and pathogenesis of Alzheimer's disease (AD) are mainly renal hypoplasia,brain turbidity endogenous,and brain damage caused by poison. Combining the theoretical foundation of traditional Chinese medicine with basic modern research,we intend to explore the guiding significance of the theory of turbid blood,turbid brain and brain toxicity in the prevention and treatment of AD. Turbid blood is a pathological state before the onset of AD. One of the specific manifestations of turbid brain-brain toxicity is the excessive deposition of Aβ and hyperphosphorylation of Tau protein,and naoluo refers to the neurovascular unit(NVU);Aβ and Tau protein,are toxic to the brain;at the same time,naoluo damage can also increase the production of turbid blood-brain toxicity. Clinical treatment methods should be based on Yishen Qudu.

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