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| Clinical study on the treatment of early COVID-19 based on Lianhua Qingwen Capsule with integrated Chinese and Western medicine |
| Hits 1231 Download times 759 Received:January 03, 2021 |
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| DOI
10.11656/j.issn.1672-1519.2021.10.03 |
| Key Words
COVID-19;Lianhua Qingwen Capsule;Chinese patent medicine;fever;fatigue |
| Author Name | Affiliation | E-mail | | TIAN Yong | Tianjin Haihe Hospital, Tianjin Institute of Respiratory Diseases, Tianjin 300350, China | | | MA Zhaorun | Tianjin Haihe Hospital, Tianjin Institute of Respiratory Diseases, Tianjin 300350, China | 18920180131@qq.com | | BI Yingfei | First Teaching Hosipital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China | | | SUN Hongyuan | First Teaching Hosipital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China | | | ZHU Zhengang | First Teaching Hosipital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China | | | SU Lishuo | First Teaching Hosipital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China | | | ZHANG Qixiu | Tianjin Haihe Hospital, Tianjin Institute of Respiratory Diseases, Tianjin 300350, China | |
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| Abstract
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| [Objective] To evaluate the clinical effect of Lianhua Qingwen Capsules in the early complementary treatment of the disease through the retrospective study of the patients diagnosed with COVID-19 and to provide reference for clinical treatment.[Methods] According to the treatment methods, the patients with COVID-19 in Tianjin from January 22 to February 23, 2020, were divided into Lianhua Qingwen Capsules therapy group(24 cases) and the control group(23 cases). The time of the major symptom(fever, fatigue, cough, expectoration) disappearance, the length of hospital stay, the days for temperature return to normal and clinical syndrome score were compared. [Results] Compared with the control group, the disappearance rate of cough symptoms in the therapy group was 66.7%(53.3% in the control group), the disappearance rate of fatigue symptoms was 100%(42.1% in the control group), the disappearance rate of expectoration symptoms was 33.3%(66.7% in the control group), and the disappearance rate of fatigue symptoms intwo groups was statistically significant(P<0.05). The disappearance rate of fever symptoms in both groups was 100%. The number of days for body temperature to return to normal in the therapy group was(3.5±1.8) d and that in the control group was(6.8±3.1) d. The difference between two groups was statistically significant(P<0.05). The improvement rate of CT images in the treatment group was 87.5%, and the control group was 78.2%. The difference was statistically significant(P<0.05). The clinical symptom score of the therapy group was significantly improved compared with the control group, and the difference was statistically significant(P<0.05). [Conclusion] Lianhua Qingwen Capsules(Granules) in the early stage of patients with COVID-19 can effectively reduce the clinical symptoms and the CT performance, shorten the time of temperature return to normal, and provide clinical research evidence for combination of western and traditional Chinese medicine more closer and more convenient. |
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