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| Study on the traditional Chinese medicine syndrome elements characteristics of fatigue symptom in Parkinson's disease |
| Hits 1294 Download times 1271 Received:June 10, 2021 |
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| DOI
10.11656/j.issn.1672-1519.2021.10.08 |
| Key Words
fatigue symptom in Parkinson's disease;traditional Chinese medicine syndrome elements;risk factors |
| Author Name | Affiliation | E-mail | | YAO Xuan | The 3th Area of Encephalopathy Departrnent, Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China | | | SHI Jin | The 3th Area of Encephalopathy Departrnent, Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China | | | LI Ting | The 3th Area of Encephalopathy Departrnent, Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China | | | QIN Bin | Beijing Hospital, Beijing 100730, China | | | XIAO Weizhong | Third Hospital of Peking University, Beijing 100191, China | | | TIAN Jinzhou | The 3th Area of Encephalopathy Departrnent, Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China | jztian@hotmail.com |
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| Abstract
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| [Objective] To study the traditional Chinese medicine(TCM) syndrome elements characteristics of Parkinson's disease fatigue. [Methods] The 83 Parkinson's disease patients were divided into fatigue group (PFS-16 ≥ 3.3, 32 cases) and non-fatigue group (PFS-16<3.3, 51 cases) according to the Parkinson's fatigue scale (PFS-16) score. TCM syndrome elements of two groups were diagnosed by the pattern element scale of Parkinson's disease (PD-PES-13). The difference in the score and ratio of TCM syndrome elements in the two groups were compared, and the Logistic regression was used to calculate the risk of TCM syndrome elements on Parkinson's disease fatigue. [Results] The ratio of spleen deficiency syndrome and blood deficiency syndrome in fatigue group were significantly higher than those in non-fatigue group (P<0.05 or P<0.01). The scores of spleen deficiency syndrome, blood deficiency syndrome and qi deficiency syndrome elements in fatigue group were significantly higher than those in non-fatigue group (P<0.05 or P<0.01). The ratio of spleen deficiency plus marrow reduction compound syndrome elements, spleen deficiency plus blood deficiency compound syndrome elements and kidney deficiency plus yin deficiency compound syndrome elements in fatigue group were significantly higher than those in non-fatigue group(P<0.05 or P<0.01). Spleen deficiency and blood deficiency syndrome elements were dangerous to the onset of Parkinson's disease fatigue (OR=3.500, P=0.008;OR=2.678, P=0.038);spleen deficiency plus marrow reduction, spleen deficiency plus blood deficiency and kidney deficiency plus yin deficiency compound syndrome elements were dangerous to the onset of Parkinson's disease fatigue (OR=6.000, P<0.001;OR=2.923, P=0.022;OR=2.679, P=0.034). [Conclusion] The main syndrome elements of Parkinson's disease fatigue are spleen deficiency, blood deficiency, and compound syndrome elements:spleen deficiency plus blood deficiency, spleen deficiency plus marrow reduction, kidney deficiency plus yin deficiency, and they may be risk factors for its onset. |
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