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| Investigate of effect in abdominal acupuncture combined with scalp acupuncture on perimenopausal insomnia and its mechanism |
| Hits 1207 Download times 659 Received:July 20, 2021 |
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| DOI
10.11656/j.issn.1672-1519.2021.10.15 |
| Key Words
perimenopausal insomnia;abdominal acupuncture;scalp acupuncture;polysomnography;estrogen;monoamine neurotransmitter |
| Author Name | Affiliation | | HUANG Wenxiong | Department of Traditional Chinese Medicine Rehabilitation, The Central Hospital of Bao'an District, Shenzhen 518101, China | | YU Xiumei | Department of Traditional Chinese Medicine Rehabilitation, The Central Hospital of Bao'an District, Shenzhen 518101, China | | ZENG Xiaohong | Department of Traditional Chinese Medicine Rehabilitation, The Central Hospital of Bao'an District, Shenzhen 518101, China |
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| Abstract
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| [Objective] To investigate the effect of abdominal acupuncture combined with scalp acupuncture on perimenopausal insomnia (PMI). [Methods] The 90 patients with PMI were divided into two groups according to the random number table method, with 45 cases in each group. The control group were treated with estazolam tablets and oryzanol tablets orally for 8 weeks. The treatment group were treated with abdominal acupuncture combined with scalp acupuncture for 8 weeks. Pittsburgh sleep quality index (PSQI), Epworth Sleepiness Scale (ESS) and modified Kupperman (KMI) scores were compared between two groups before and after treatment, and the polysomnography (PSG) test indexes and serum estradiol (E2), follicle stimulating hormone (FSH), luteinizing hormone (LH) were compared between two groups. Serum 5-hydroxytryptamine (5-HT) and noradrenaline (NE) were determinedby chemilumin escence method. [Results] PSQI, ESS and KMI scores of the treatment group were lower than those of the control group after treatment(P<0.01), and total sleep time (TST), sleep maintenance rate (SE) were higher than those of the control group (P<0.01).Wake time (AWT), wake times (AT), sleep latency (SL) were lower than those of the control group (P<0.01). S1 and S2 of slow wave sleep (NREM) were lower than those of the control group (P<0.05 or P<0.01), and S3 + 4, fast wave Sleep (REM) was higher than the control group (P<0.05 or P<0.01). Serum E2, 5-HT in the treatment group were higher than that in the control group (P<0.01), FSH, LH, NE in the treatment group were lower than that in the control group(P<0.01).The difference was statistically significant. [Conclusion] Abdominal acupuncture combined with scalp acupuncture can improve the sleep process and sleep quality of PMI patients. The mechanism may be related to the regulation of estrogen secretion, the increase of 5-HT synthesis and secretion, and the inhibition of NE release. |
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