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| Clinical observation of Zini Rongfu Xiaobai Ointment in treating lichen simpex chronicus |
| Hits 697 Download times 507 Received:August 07, 2021 |
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| DOI
10.11656/j.issn.1672-1519.2021.12.08 |
| Key Words
external treatment of traditional Chinese medicine;Rongfu Xiaobai ointment;damp-heat symptom;lichen simpex chronicus |
| Author Name | Affiliation | E-mail | | ZHAO Jianing | Hebei University of Chinese Medicine, Shijiazhuang 050090, China | | | ZHANG Ye | Hebei University of Chinese Medicine, Shijiazhuang 050090, China | | | SU Jian | Second Department of Gynecology, Shijiazhuang Hospital of Traditional Chinese Medicine, Shijiazhuang 050000, China | xd222@sina.com |
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| Abstract
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| [Objective] To evaluate the clinical effect of Rongfu Xiaobai ointment in the treatment of Lichen simpex chronicus, and analyze its clinical efficacy and safety.[Methods] The 80 patients with Lichen simpex chronicus (damp-heat type) who were treated in our clinic were divided into the treatment group and the control group with 40 cases in each group using a random number table method. The treatment group was given Rongfu Xiaobai ointment rubbing treatment, and the control group was given hydrocortisone butyrate cream rubbing treatment. The changes of patients' symptoms and signs were observed during 1 and 2 months of treatment, the changes in traditional Chinese medicine(TCM) syndrome scores, absolute counts of T lymphocyte subsets, and adverse reactions before and 2 months of treatment were recorded.[Results] There was no significant difference in the clinical efficacy index between two groups after treatment (P>0.05). After treatment for 1 month and 2 months, the pruritus symptoms, skin elasticity, lesion area score, and skin color score of the two groups were decreased. The treatment group in the improvement of skin elasticity and skin color was better than that of the control group (P<0.05). After treatment, the absolute counts of serum T lymphocyte subsets of the two groups were significantly different from those before treatment (P<0.05), and the treatment group was better than the control group(P<0.05). After treatment, comparing the total scores of TCM syndromes between the two groups, the differences between two groups were statistically significant (P<0.05), and the differences between two groups after treatment were statistically significant (P<0.05).[Conclusion] In treating Lichen simpex chronicus, Rongfu Xiaobai ointment has a good effect in improving the skin elasticity and skin color of the patient, and it can improve the immune function of the patient and has good safety. |
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