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| Active polysaccharides regulating bile acids throughintestinal tract |
| Hits 747 Download times 564 Received:August 25, 2021 |
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| DOI
10.11656/j.issn.1672-1519.2022.01.28 |
| Key Words
polysaccharide;bile acid;intestine;intestinal flora;bile acid transporter |
| Author Name | Affiliation | E-mail | | DI Jingrui | The State Key Laboratory of Component-based Chinese Medicine, Research Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | SHANG Fei | The State Key Laboratory of Component-based Chinese Medicine, Research Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | YANG Li | The State Key Laboratory of Component-based Chinese Medicine, Research Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | YANG Miaojie | The State Key Laboratory of Component-based Chinese Medicine, Research Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | ZHAO Xin | The State Key Laboratory of Component-based Chinese Medicine, Research Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | ZHANG Peng | The State Key Laboratory of Component-based Chinese Medicine, Research Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | zhp8270@sina.com |
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| Abstract
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| Polysaccharides are important component of human diet and have rich biological activities. Bile acids are the major component of intestinal lipid digestibility and the key signaling factor of metabolic homeostasis，which have crucial impact on human health. Studies have shown that some active polysaccharides can regulate the level of bile acids in vivo. Bile acids are reabsorbed，metabolized and excreted through the intestine，and the biological activities of polysaccharides are also closely related to the intestinal tract. This article reviews the research progress of active polysaccharides regulating bile acids from the aspects of adjusting intestinal bile acid transporters，regulating gut microbiota and binding directly to the bile acids. |
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