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| Exploration of clinical experience of Professor TAN Jinchuan in the treatment of membranous nephropathy by data mining method |
| Hits 606 Download times 354 Received:November 26, 2021 |
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| DOI
10.11656/j.issn.1672-1519.2022.03.16 |
| Key Words
membranous nephropathy;cluster analysis;association rules;data mining;medication experience |
| Author Name | Affiliation | E-mail | | GAO Fei | Hebei University of Chinese Medicine, Shijiazhuang 050200, China | | | WANG Zeze | Hebei University of Chinese Medicine, Shijiazhuang 050200, China | | | YANG Bing | Hebei University of Chinese Medicine, Shijiazhuang 050200, China | | | TAN Jinchuan | Hebei Provincial Hospital of Traditional Chinese Medicine, Shijiazhuang 050011, China | 1955981973@qq.com |
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| Abstract
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| To explore Professor TAN Jinchuan's experience in the treatment of membranous nephropathy and summarize its characteristics and rules. The outpatient medical records of treating membranous nephropathy of Professor TAN Jinchuan were collected,the data were input with EpiData 3.1 software package,and the statistical analysis and data mining of traditional Chinese medicine prescriptions included in the medical records were carried out with Excel 2013,SPSS 19.0 and R 3.5 software package. 353 prescriptions of traditional Chinese medicine were finally included,among which 163 were involved,with a total frequency of 5 273. The most commonly used traditional Chinese medicines are Astragali Radix,Chuanxiong Rhizoma,Angelicae Sinensis Radix,Poria,Sinomenii Caulis,of which Astragali Radix is the core drug. The drugs with sweet taste,warm nature and liver meridian tropism are the most. Tonic drugs and promoting blood circulation to remove blood stasis are widely used. In addition,the most commonly used drug pairs and combinations are excavated. It is suggested that the treatment of membranous nephropathy should be based on the deficiency of both spleen and kidney,water dampness,heat dampness and blood stasis. According to the characteristics of pathogenesis of membranous nephropathy,we should dialectically seek the cause,treat the disease and seek the root,reuse astragalus,make good use of insect drugs,and flexibly form prescriptions,so as to improve the clinical efficacy and delay the progress of the disease. |
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