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Analysis on the medication and efficacy of integrated traditional Chinese and Western medicine in the treatment of COVID-19 in Tianjin area
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DOI   10.11656/j.issn.1672-1519.2022.04.04
Key Words   Tianjin area;COVID-19;integrated traditional Chinese and Western medicine;curative effect;association rule
Author NameAffiliationE-mail
BI Yingfei First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
SUN Hongyuan First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
ZHAO Guoyuan First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
SUN Binxu First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
JIN Yue First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
ZHANG Weifeng First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
HAN Yaowei First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
MA Yuntao First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
SU Lishuo First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
SU Quan First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
WANG Xianliang First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
TIAN Yong Tianjin Haihe Hospital, Tianjin 300350, China  
MA Zhaorun Tianjin Haihe Hospital, Tianjin 300350, China  
ZHU Zhengang First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
LIU Min First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
WU Shentao First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
LIU Wei First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
JIA Yingjie First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
YANG Hongtao First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
SHI Zhexin First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
WANG Qiang First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
LI Bin First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
LI Xinmin First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
LIU Xinqiao First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China  
MAO Jingyuan First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China jymao@126.com 
ZHANG Boli First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China zhangbolipr@163.com 
Abstract
    [Objective] To summarize the medication and efficacy of integrated traditional Chinese and Western medicine in the treatment of COVID-19 in Tianjin. [Methods] The medication uses and clinical efficacy evaluation of 132 local confirmed cases of COVID-19 who met discharge standards after treatment with integrated traditional Chinese and Western medicine in Tianjin were summarized. [Results] Among the 132 patients,there were more males than females. The diseased population was mainly the middle-aged,and the types were normal and severe types mainly. Spleen and stomach symptoms such as diarrhea,anorexia,nausea was common. At the same time,the symptoms of dampness invading the lung such as having fever,cough,expectoration,and hypohidrosis were also common. There were also heat syndromes such as yellow urine,dry mouth,bitter mouth,original deficiency syndromes such as fatigue and shortness of breath,and blood stasis syndromes such as dark red tongue. In traditional Chinese medicine treatment,the most commonly used drugs were Pinellia ternata,Poria cocos,dried Tangerine Peel,Magnolia officinalis,Atractylodis Macrocephalae Rhizoma,Knotweed,Medicated Leaven,Semen Coicis,Amomi Fructus Rotundus,Herba Agastaches,Coptis chinensis and Aster tataricus. In Western medicine treatment,the most commonly used drugs were antiviral drugs such as ritonavir and arbidol,and the combination of the two drugs were also high (59.1%). The number of patients who use other drugs such as recombinant human interferon α-2b and acetylcysteine tablets are more than 50%. Quinolone antibiotics were also used. After the systematic combination of traditional Chinese and western medicine treatment,the patient's symptoms such as strong heat,aversion to cold,headache,heavy body disappeared up to 100%. The disappearance rate of symptoms such as anorexia,nausea,low-grade fever,expectoration,hypohidrosis,bitter mouth,yellow urine,less breath,lazy talk,and shortness of breath also reached more than 80%. The clinical symptoms and the quality of life improved significantly. Many laboratory indicators showed positive trend. [Conclusion] Integrated traditional Chinese and western medicine treatment of COVID-19 patients can significantly improve the patients' clinical symptoms and quality of life,and promote the negative result of nucleic acid,recovery and discharge from hospital.

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