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Research progress in the treaditional Chinese madicine treatment of insomnia by adjusting intestinal flora based on microbiota-gut-brain axis theory
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DOI   10.11656/j.issn.1672-1519.2022.04.25
Key Words   microbiota-gut-brain axis;gut-brain axis;gut microbiota;insomnia;traditional Chinese medicine
Author NameAffiliationE-mail
HUANG Qian The Fourth Clinical Medicine College of Guangzhou University of Chinese Medicine, Shenzhen 518033, China  
ZENG Lin The Fourth Clinical Medicine College of Guangzhou University of Chinese Medicine, Shenzhen 518033, China  
WANG Gaoxiang Nanjing University of Chinese Medicine, Nanjing 210000, China  
LI Huilin The Fourth Clinical Medicine College of Guangzhou University of Chinese Medicine, Shenzhen 518033, China
Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen 518033, China 
sztcmlhl@163.com 
Abstract
    Insomnia is a clinical disease which is prevalent but difficult to cure. The microbiota-gut-brain axis has been shown to be associated with many systemic diseases,such as neurological,digestive,endocrine,respiratory diseases. In recent years,some studies have shown that gut microbiota is closely related to insomnia,and continuous clinical and experimental studies have shown that traditional Chinese medicine(TCM) can improve insomnia by regulating intestinal flora instability. This paper discusses the overview of the microbiota-gut-brain axis,the theoretical basis of TCM and the research progress of regulating intestinal flora in TCM based on the theory of microbiota-gut-brain axis and so on,in order to provide new ideas for the treatment of insomnia.

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