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Clinical observation of Xuanfei Baidu Granule in the treatment of COVID-19(Omicron)
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DOI   10.11656/j.issn.1672-1519.2022.05.01
Key Words   Omicron;COVID-19;Xuanfei Baidu Granule;clinical study
Author NameAffiliationE-mail
FENG Limin Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China  
LIU Xiaoya First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China  
ZHANG Lei Tianjin Hospital, Tianjin 300210, China zhangleitj2008@163.com 
Abstract
    [Objective] The research is to analyze the clinical efficacy of Xuanfei Baidu Granules in the treatment of COVID-19(Omicron) infection.[Methods] The 40 Omicron cases in the ward of Tianjin Haihe Hospital were treated with Xuanfei Baidu Granules,the efficacy of which was assessed by such indicators as the number of days between the positive nucleic acid test(NAT) and negative NAT,clinical physicochemical indexes,imaging examinations,the changes of traditional Chinese medicine syndrome score. The study then discussed the clinical efficacy of Xuanfei Baidu Granules in the treatment of COVID-19(Omicron) cases.[Results] All the 40 patients were discharged from the hospital after taking Xuanfei Baidu Granules,with a cure rate of 100%. And none of them turned into severe or critical type. The nucleic acid of 40 patients turned positive to negative with the average time of 10.2 days and medium duration of 10 days. And 29 of them turned around after CT imaging treatment,with an improvement rate of 72.5%. In terms of clinical physicochemical indicators,compared with admitted to hospital,the absolute lymphocyte value and lymphocyte percentage increased,the oxygen saturation in blood gas analysis increased,and C-reactive protein,interleukin-6 and PCT were all lower than the time of admission. In safety indexes,there was no adverse reaction found with Xuanfei Baidu Granules. As for traditional Chinese medicine syndrome score,all patients' clinical symptoms of cough,sore throat,dry throat,fever,coughing sputum,nasal congestion,runny nose,headache,itchy throat and fatigue disappeared after treatment,with a total effective rate of 100%.[Conclusion] Xuanfei Baidu Granules can improve the lymphocyte level and reduce the PCT of patients,while improving clinical symptoms and shortening the duration of negative NAT.

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