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Analysis of traditional Chinese medicine constitution types and clinical characteristics of 85 discharged patients with COVID-19 in Tianjin
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DOI   10.11656/j.issn.1672-1519.2022.07.06
Key Words   COVID-19;TCM constitution;T lymphocyte subsets;lung CT;rehabilitation
Author NameAffiliation
LUO Mingchi Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China 
FENG Jihong Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China 
ZHOU Shengyuan Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China 
ZHANG Shuo Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China 
FU Kun Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China 
WANG Kai Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China 
NI Daoyan Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China 
LIU Huan Tianjiin University of Traditional Chinese Medicine, Tianjin 301617, China 
ZAN Shujie Tianjiin University of Traditional Chinese Medicine, Tianjin 301617, China 
Abstract
    [Objective] To collect the physical examination and traditional Chinese medicine(TCM) constitution identification data of discharged patients with COVID-19 in Tianjin,analyze their clinical characteristics and TCM constitution types,and provide reference for further TCM rehabilitation of patients with COVID-19.[Methods] A cross-sectional study was carried out in 85 patients with COVID-19 in Tianjin who were discharged from hospital for 12 to 17 months. Antibody examination,blood routine examination,biochemical indexes,T lymphocyte subsets,echocardiography,liver,gallbladder,pancreas,spleen,urinary system ultrasound,lung CT,and TCM constitution identification were performed and the results were analyzed.[Results] There were 61 patients (71.76%) with IgG(+) in 85 convalescent patients. Among T lymphocyte subsets,CD45+ Lym decreased in 70 cases (82.36%),CD3+ decreased in 60 cases (70.59%),CD3+CD4+ decreased in 57 cases (67.06%),and CD3+CD8+ decreased in 40 cases (47.06%). The abnormal manifestations of lung CT included 78 cases of increased lung texture,24 cases of pulmonary nodules,9 cases of mediastinal lymph node shadow,3 cases of ground glass shadow,3 cases of pulmonary fibrosis,and 3 cases of emphysema. The main constitution types of TCM constitution identification are balanced constitution(47.62%),followed by blood stasis constitution (17.85%),qi deficiency constitution (15.48%) and dampness-heat constitution (8.33%).[Conclusion] There are still some sequelae such as decreased immune function and chronic pulmonary inflammatory response in patients with COVID-19 after 12 to 17 months of discharge rehabilitation. Although the overall TCM constitution type tends to be balanced constitution,blood stasis,qi deficiency and dampness heat constitution still coexist,suggesting that traditional Chinese medicine can carry out long-term rehabilitation for patients with COVID-19 from the TCM constitution type and need to strengthen follow-up.

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