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Based on the theory of "deficiency and stasis" to explore the clinical study of tonifying kidney and activating blood circulation in the treatment of type Ⅱ osteoporotic hip fracture
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DOI   10.11656/j.issn.1672-1519.2022.09.09
Key Words   tonifying kidney and promoting blood circulation;kidney deficiency;blood stasis;type Ⅱ osteoporosis;hip fracture
Author NameAffiliation
JING Jingti Department of Orthopaedics and Traumatology, Shenzhen Luohu People's Hospital, Shenzhen 518001, China 
ZHOU Jin Department of Orthopaedics and Traumatology, Shenzhen Luohu District Hospital of Chinese Medicine, Shenzhen 518001, China 
ZHANG Xin Department of Orthopaedics and Traumatology, Shenzhen Luohu District Hospital of Chinese Medicine, Shenzhen 518001, China 
JIANG Haoming Department of Orthopaedics and Traumatology, Shenzhen Luohu People's Hospital, Shenzhen 518001, China 
ZHAO Zhiheng Encephalopathy Acupuncture Center, Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjing 300250, China 
ZHANG Lin Department of Orthopaedics and Traumatology, Shenzhen Luohu People's Hospital, Shenzhen 518001, China 
WANG Zhiqiang Department of Orthopaedics and Traumatology, Shenzhen Luohu District Hospital of Chinese Medicine, Shenzhen 518001, China 
LIU Dehua Department of Orthopaedics and Traumatology, Shenzhen Luohu District Hospital of Chinese Medicine, Shenzhen 518001, China 
ZHANG Weihong Department of Orthopaedics and Traumatology, Shenzhen Luohu District Hospital of Chinese Medicine, Shenzhen 518001, China 
ZHANG Junbo Department of Orthopaedics and Traumatology, Shenzhen Luohu District Hospital of Chinese Medicine, Shenzhen 518001, China 
Abstract
    [Objective] To explore the clinical effect of tonifying kidney and activating blood under the guidance of "deficiency and stasis" theory in the treatment of type Ⅱ osteoporotic hip fracture.[Methods] From June 2020 to March 2021,80 elderly patients with unilateral femoral neck or intertrochanteric fresh closed fractures treated with internal fixation were enrolled.Randomly divided into treatment group and control group according to random number table method,40 cases in each group.On the basis of conventional treatment,the treatment group was given Qianggu Huoxue Decoction orally,and the control group was given traditional Chinese medicine orally in three stages,the course of treatment was 6 months.Observe and record hip radiographs were taken before surgery and 1 to 6 months after surgery to evaluate fracture healing in both groups.Bone mineral density of L1-4 and healthy femoral neck and bone metabolism indexes (T-PINP,β-CTX,N-MID) were examined 3 and 6 months after operation.Hip function and quality of life were evaluated 6 months after surgery.[Results] The clinical healing time of the treatment group was shorter than that of the control group,and the difference was statistically significant (P<0.05).The comparison of L1-4 bone mineral density between 2 groups showed that 3 and 6 months after surgery,and the treatment group was significantly better than the control group (P<0.05).Comparison of bone mineral density of healthy femoral neck between the two groups showed that 3 months after surgery,and the difference was not statistically significant (P>0.05),and 6 months after surgery,and the treatment group was significantly better than the control group (P<0.05).At 3 and 6 months after surgery,T-PINP in the treatment group was higher than that in the control group,and the difference was statistically significant (P<0.05);β-CTX was lower than that in the control group,and the difference was statistically significant (P<0.05);N-MID change was not significant (P>0.05).The 3 months after surgery,Harris score of the control group was better than that of the control group,and the difference was statistically significant (P<0.05),and there was no significant difference in Harris score of the two groups 6 months after surgery (P>0.05).The EQ-5D index and EQ-VAS score of the treatment group were better than those of the control group at 6 months after surgery,and the differences were statistically significant (P<0.05).[Conclusion] Tonifying kidney and promoting blood circulation can promote hip fracture healing,improve bone density,regulate bone metabolism,improve clinical efficacy and quality of life.

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