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The homogenization of standard slices of Descurainiae Semen and stir-fried Descurainiae Semen
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DOI   10.11656/j.issn.1672-1519.2022.09.19
Key Words   Descurainiae Semen;stir fried Descurainiae Semen;homogenization;orthogonal experiment
Author NameAffiliationE-mail
DING Mingya Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
ZHANG Yaqian Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
YANG Yuqiao Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
LI Jin Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
HE Jun Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
CHANG Yanxu Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China tcmcyx@126.com 
Abstract
    [Objective] To optimize the best homogenization of the standard decoction pieces of Descurainiae Semen and stir-fried Descurainiae Semen.[Methods] The orthogonal experiment L9(34) was designed in terms of powder yield,the total content of three flavonoids (Quercetin-3-O-β-D-glucopyranose-7-O-β-D-gentiandiglycoside,Quercetin-3-O-β-D-glucopyranoside and Isorhamnetin-3-O-β-D-glucopyranose) and the total peak areas in the fingerprint as marker,and the three factors of feeding amount,single crushing time,and crushing times were investigated to optimize the homogenization for standard pieces of Descurainiae Semen and stir fried Descurainiae Semen.[Results] The optimum grinding process of Descurainiae Semen:dosage 150 g,single crushing time 10 seconds,crushing 4 times.The best grinding of stir fried Descurainiae Semen:dosage 100 g,single crushing time 10 seconds,crushing 3 times.[Conclusion] The homogenization process by orthogonal experiment was right,reasonably practicable,which provided a reference for the quality control of standard pieces of Descurainiae Semen and stir fried Descurainiae Semen.What's more,the homogenization process prepared the ground for the formulation of homogenization technical specifications of standard pieces.

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