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| Effect of Bushen Huatan Huoxue Decoction combined with acupuncture on ovulation induction function and sex hormone levels in patients with polycystic ovary syndrome |
| Hits 623 Download times 293 Received:July 15, 2022 |
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| DOI
10.11656/j.issn.1672-1519.2022.10.14 |
| Key Words
polycystic ovarian syndrome;recipe for tonifying the kidney;resolving phlegm and activating blood;acupuncture;sex hormones;ovulation function |
| Author Name | Affiliation | | ZHANG Yunfeng | Expert Clinic of Traditional Chinese Medicine, Cangzhou Hospital of Integrated TCM-WH·
Hebei, Cangzhou 061000, China | | WANG Xiaojie | Department of Gynecology, Handan Maternal and Child Health Hospital, Handan 056000, China | | ZHANG Yanmin | Department of Internal Medicine, People's Hospital of Jingxing Mining Area, Shijiazhuang 050100, China |
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| Abstract
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| [Objective] To explore the effect of Bushen Huatan Huoxue Decoction combined with acupuncture in the treatment of polycystic ovarian syndrome (PCOS).[Methods] The124 patients with PCOS admitted to our hospital from June 2020 to June 2021 were selected as the research objects.They were divided into the group A and the group B by a random number table method and double blind method,with 65 cases in each group.With clomiphene citrate capsules,the group B was treated with Bushen Huatan Huoxue Decoction combined with acupuncture and moxibustion.During the treatment,2 cases in group A were fell off,and 2 cases in group B were fell off.A total of 63 cases in each group entered into statistical analysis.The levels of follicle stimulating hormone (FSH),luteinizing hormone (LH),total testosterone (T),estradiol (E2) and endometrial thickness during ovulation were measured before and after treatment,and the symptoms of the patients were scored by the traditional Chinese medicine (TCM) syndrome score,statistics of patients'ovulation rate,pregnancy rate and incidence of adverse reactions.[Results] After treatment,the scores of LH and T levels,menstrual abdominal pain,dizziness,tinnitus,waist and knee pain,and apathy in the two groups were reduced,and the group B was lower than the group A (P<0.05),and the E2 level and endometrial thickness were both increased and the E2 level of the group B was higher than that of the group A (P<0.05).The ovulation rate and pregnancy rate of the group B were higher than those of the group A (P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05).[Conclusion] Bushen Huatan Huoxue Decoction combined with acupuncture can effectively improve the level of sex hormones in patients with PCOS,relieve clinical symptoms,increase ovulation rate and pregnancy rate,safe and effective. |
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