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| A randomized controlled study on Tongmai Yangxin Pill in the treatment of bradyarrhythmia (qi-yin deficiency syndrome) |
| Hits 533 Download times 861 Received:December 28, 2022 |
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| DOI
10.11656/j.issn.1672-1519.2023.03.03 |
| Key Words
Tongmai Yangxin Pill|bradyarrhythmia|qi-yin deficiency syndrome|clinical observation |
| Author Name | Affiliation | E-mail | | CAI Xiaoyue | Department of Cardiology, Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China | | | LI Tian | Department of Cardiology, Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China | | | WEN Yu | Health Management Center, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 301617, China | | | ZHANG Yunjiao | Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | ZHAO Yingqiang | Department of Cardiology, Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China | zhaoyingqiang1000@126.com |
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| Abstract
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| [Objective] To observe the clinical effect of Tongmai Yangxin Pills on bradyarrhythmia(qi-yin deficiency syndrome).[Methods] The 72 subjects with bradyarrhythmia were included and divided into experimental group and control group randomly. The experimental group was treated with Tongmai Yangxin Pills,while the control group was treated with placebo for 8 weeks. The differences of total curative effect,heart rate index,total curative effect of traditional Chinese medicine(TCM) syndrome and single symptom of TCM between the two groups were observed.[Results] Tongmai Yangxin Pills has a good therapeutic effect on the heart rate of slow arrhythmia. The average heart rate,total heart rate,slowest heart rate and fastest heart rate of experimental group were increased compared with before treatment (P<0.05). The total effective rate of dynamic electrocardiogram was 83.9% in experimental group and 43.3% in control group,the experimental group was higher than the control group (P<0.05). In TCM syndrome,the total effective rate of experimental group was 90.3%,it was significantly higher than the control group with 43.3%(P<0.05);The efficacy of single symptom in the experimental group was better than that in the control group in improving symptoms such as palpitation,shortness of breath and lazy speech,fatigue and fatigue,hyper sweating,five irritability fever,dry mouth and dizziness(P<0.05),both groups had good efficacy in improving the symptoms of insomnia and multiple dreams,with no statistical significance(P>0.05).[Conclusion] Tongmai Yangxin Pills has a significant effect in the treatment of patients with bradyarrhythmia (qi-yin deficiency syndrome),which can effectively increase heart rate and improve clinical symptoms. |
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