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| Research progress on antitumor pharmacological action and clinical application of traditional Chinese medicine Euphorbia helioscopia L. and its compound preparations |
| Hits 597 Download times 548 Received:January 20, 2023 |
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| DOI
10.11656/j.issn.1672-1519.2023.03.20 |
| Key Words
Euphorbia helioscolia L.|antitumor pharmacological action|clinical application |
| Author Name | Affiliation | | WANG Dong | Department of Pharmacy, Tianjin Medical University Cancer Institue & Hospital, Tianjin Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center for Cancer, Tianjin Clinical Research Center for Malignant, Tianjin 300060, China
Department of Pharmacy, Tianjin Cancer Hospital Airport Hospital, Tianjin 300308, China | | ZHANG Xiangyu | Department of Pharmacy, Tianjin Cancer Hospital Airport Hospital, Tianjin 300308, China | | SHAO Yingying | Chinese Medicine Research Institue, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | YU Haiyang | Chinese Medicine Research Institue, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China |
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| Abstract
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| Euphorbia helioscolia L. is a perennial herb of Euphorbiaceae. The efficacy is to promote diuresis and detumescence,dispel phlegm and fever,kill insects and itch,and disperse knots. Through modern scientific means,a series of pharmacodynamic substances in Euphorbia helioscolia have been identified. Pharmacological activity studies show that Euphorbia helioscolia and its compound preparations have certain anti-tumor effects at the cellular level and animal level,especially for lung adenocarcinoma,liver cancer,gastric cancer and breast cancer. In practical clinical applications,Zeqi Decoction and its modified formulas or combined chemotherapy and other drugs are often used to assist in the treatment of liver cancer,lung cancer,breast cancer,malignant ascites and other diseases,In this paper,the pharmacological effects and clinical treatment of Euphorbia helioscolia and its compound preparations in antitumor at home and abroad in recent years were summarized,in order to provide ideas for experimental research,clinical treatment and development of Euphorbia helioscolia and its formula. |
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