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Research progress of kidney-tonifying herbs and anti-aging mechanism of traditional Chinese medicine active ingredients
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DOI   10.11656/j.issn.1672-1519.2023.04.22
Key Words   tonifying kidney;traditional Chinese medicine;Chinese medicine compound;anti-aging;mechanism of action
Author NameAffiliationE-mail
LI Shaokang College of Traditional Chinese Medicine, Henan University of Chinese Medicine, Zhengzhou 450046, China  
ZHAO Yun College of Traditional Chinese Medicine, Henan University of Chinese Medicine, Zhengzhou 450046, China  
GAO Na College of Traditional Chinese Medicine, Henan University of Chinese Medicine, Zhengzhou 450046, China  
YAO Tao College of Traditional Chinese Medicine, Henan University of Chinese Medicine, Zhengzhou 450046, China  
ZHANG Yunke School of Rehabilitation Medicine, Henan University of Chinese Medicine, Zhengzhou 450046, China  
CHE Zhiying College of Traditional Chinese Medicine, Henan University of Chinese Medicine, Zhengzhou 450046, China chezy365@126.com 
Abstract
    Aging is a life stage that involves many aspects including organs, cells and tissues, as well as various age-related diseases. Traditional Chinese medicine believes that kidney deficiency is closely related to aging, and tonifying kidney plays an important role in delaying aging. Traditional Chinese medicine can delay aging in multiple ways, multiple targets and multiple effects. This paper summarizes the mechanism of kidney-tonifying formulas and effective components of traditional Chinese medicine in delaying aging research by reviewing the literature. It can regulate oxidative stress, endoplasmic reticulum stress, apoptosis, immune response, stem cell proliferation and differentiation, and neuroprotection, so as to provide reference for the anti-aging research of traditional Chinese medicine.

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