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Characteristics and traditional Chinese medicine syndrome of “long-COVID” of 746 COVID-19 patients in Tianjin
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DOI   10.11656/j.issn.1672-1519.2023.05.03
Key Words   COVID-19;Omicron;long-COVID;traditional Chinese medicine syndrome;rehabilitation
Author NameAffiliationE-mail
WANG Kai Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China  
JIANG Nan Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China  
SUN Xue Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
Ni Daoyan Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China  
TIAN Ying Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China  
SUN Xiaozhuo Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China  
ZAN Shujie Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
ZHANG Shuo Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China  
ZHOU Shengyuan Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China  
FENG Jihong Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China  
FU Kun Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China  
LUO Mingchi Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China luomingchi2008@163.com 
Abstract
    [Objective] To study the occurrence，clinical characteristics and the syndrome of traditional Chinese medicine（TCM） of COVID-19 patients in Tianjin after discharge，so as to provide evidence for the rehabilitation treatment of convalescent patients. [Methods] A total of 746 patients infected with Omicron between January and March in 2022 were followed up 3 and 6 months after discharge，and they were systematically examined at 3 months after the discharge，for blood routine，biochemical indexes，chest computed tomography （CT）. [Results] Among the 746 patients，58（7.8%） met the definition of long-COVID. The symptoms of long-COVID mainly manifested as fatigue，memory loss，difficulty to fall asleep or wake up from dreams，shortness of breath after activity，etc. Laboratory tests were basically normal. Chest CT examination of 36 people showed that 25 cases of showed increased lung texture，without obvious clinical significance；11 cases of fibrous stripes and 2 cases of pulmonary fibrosis，suggesting old injury；2 cases of emphysema which was underlying disease；9 cases of lung nodules and 1 case of ground-glass opacities，suggesting possible inflammation. The investigation of TCM syndrome found that the most common syndrome elements are spleen，heart，lung and kidney，the most common disease symptoms qi deficiency，yin deficiency，humidity，and heat. [Conclusion] The incidence of long-COVID and lung imaging damage in patients with Omicron infection after discharge is lower than that of previous strains，but the symptoms such as fatigue，memory loss，and sleep disorders still need attention. Qi and yin deficiency，accompanied with humidity（heat），qi stasis and blood stagnation is the most common TCM syndrome.

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