|
| Clinical effect of Niaoduqing Granule combined with calcium carbonate and blood perfusion in the treatment of hyperphosphatemia after hemodialysis |
| Hits 675 Download times 1529 Received:December 25, 2022 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1672-1519.2023.05.04 |
| Key Words
chronic kidney disease;hemodialysis;hyperphosphatemia;blood perfusion;Niaoduqing Gramule |
| Author Name | Affiliation | | LI Xiong | Xicheng District Guangwai Hospital Guangwai Hospital, Beijing 100055, China | | LIU Yanxia | Xicheng District Guangwai Hospital Guangwai Hospital, Beijing 100055, China | | ZHANG Xin | Xicheng District Guangwai Hospital Guangwai Hospital, Beijing 100055, China |
|
| Abstract
|
| [Objective] To explore the clinical effect of Niaoduqing Granule combined with calcium carbonate and blood perfusion hemoperfusion in the treatment of hyperphosphatemia after hemodialysis and its influence on the quality of life of patients. [Methods] The 101 patients were randomly divided into the observation group 51，the control group 50. Both groups were given basic treatment such as calcium carbonate and blood perfusion，the observation group added Niaoduqing Granules to the basic treatment，and the control group was given placebo of the same specification. The two groups were treated for 3 months. The clinical efficacy，inflammatory reaction，total parathyroid hormone，anemia，blood phosphorus and blood calcium of the two groups were compared. The two groups were followed up for 3 months to compare the quality of life. [Results] After treatment，the total effective rate of the observation group was higher than that of the control group （<P<0.05），CRP，IL-6，TNF-α and the levels of blood phosphorus，vitamin B12 and folic acid were lower than those of the control group （P<0.05，P<0.01），and the scores of serum ferritin and quality of life were higher than those of the control group （P<0.01）. There was no significant difference in iTPH and blood calcium levels between groups before and after treatment （P>0.05）. [Conclusion] Niaoduqing Granule combined with calcium carbonate and blood perfusion can improve the total effective rate of treatment，improve the inflammatory reaction and nutritional status，reduce the blood phosphorus level，do not affect the iPTH and blood calcium level，and improve the quality of life of patients. It is worthy of promotion. |
|
