|
| Mechanism and clinical research progress of Gancao Xiexin Decoction in the treatment of ulcerative colitis |
| Hits 485 Download times 530 Received:December 10, 2022 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1672-1519.2023.06.19 |
| Key Words
Gancao Xiexin Decoction;ulcerative colitis;inflammatory factor;intestinal mucosa;intestinal flora |
| Author Name | Affiliation | E-mail | | DING Jiuli | First Teaching Hospital to Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300193, China
Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | GUO Xiaojing | First Teaching Hospital to Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300193, China
Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | LIU Wei | First Teaching Hospital to Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300193, China | fengshiliuwei@163.com | | KA Yuxiu | First Teaching Hospital to Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300193, China
Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | LIN Fangfang | First Teaching Hospital to Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300193, China
Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | YANG Xiaoyan | First Teaching Hospital to Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300193, China | |
|
| Abstract
|
| Ulcerative colitis （UC） is a chronic，non-specific inflammatory bowel disease. The etiology may be related to environmental， genetic，immune，infectious and intestinal microbiological factors. Gancao Xiexin Decoction from treatise on febrile diseases. It is composed of prepared liquorice，scutellaria，coptis，dried ginger，ginseng，pinellia ternata and jujube，which has the effect of mediating cold and heat，eliminating ruffian and stopping profits. Modern studies have found that Gancao Xiexin Decoction alone or combined with Western medicine has significant curative effect on UC，and its mechanism involves regulating inflammatory factors，protecting intestinal mucosa and improving intestinal flora. Through reviewing relevant literature，this paper summarized and summarized the mechanism and clinical research related to the treatment of UC by Gancao Xiexin Decoction and its monomer in recent years，in order to provide theoretical basis for the treatment of UC by traditional Chinese medicine and integrated traditional Chinese and Western medicine and expand the treatment ideas. |
|
|
|
|
|
|
|
