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Modern research progress on traditional Chinese medicine syndrome types and action mechanism of traditional Chinese medicine in myocardial hypertrophy
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DOI   10.11656/j.issn.1672-1519.2023.06.20
Key Words   traditional Chinese medicine syndrome differentiation;myocardial hypertrophy;Chinese medicine treatment;protection mechanism
Author NameAffiliationE-mail
ZHAN Jiaguo Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
SONG Shaofei Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
YANG Yingxi Collage of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
LENG Ling Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Tianjin 301617, China
Haihe Laboratory of Modern Chinese Medicine, Tianjin 301617, China 
 
ZHAN Jiayi Chongqing University Cancer Hospital, Chongqing 400030, China  
WANG Qilong Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Tianjin 301617, China
Haihe Laboratory of Modern Chinese Medicine, Tianjin 301617, China 
wangqilong_00@tjutcm.edu.cn 
LI Ruiqiao Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Tianjin 301617, China 
liruiqiao@tjutcm.edu.cn 
Abstract
    Myocardial hypertrophy is an abnormal enlargement of cardiomyocytes caused by pressure or volume overload in the heart, which in turn affects the cardiac pathways of gene transcription,protein synthesis,metabolism,oxidative stress and autophagy,ultimately leading to chronic heart failure. This paper reviews the four types of traditional Chinese medicine (TCM) evidence of myocardial hypertrophy,namely qi deficiency and blood stasis,phlegm and blood stasis,qi and yin deficiency,and yang deficiency and water flooding,and their pathogenesis,as well as the research progress of TCM in the diagnosis and treatment of myocardial hypertrophy. In the hope of providing new ideas for the clinical prevention and treatment of myocardial hypertrophy.

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