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| Study on the risk and traditional Chinese medicine syndromes of cardiovascular and cerebrovascular diseases in 969 patients with metabolic syndrome |
| Hits 646 Download times 321 Received:April 20, 2023 |
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| DOI
10.11656/j.issn.1672-1519.2023.07.01 |
| Key Words
metabolic syndrome;cryptic structural model;cardiovascular and cerebrovascular disease risk |
| Author Name | Affiliation | E-mail | | WU Junliang | School of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130117, China | | | SHI Tingting | Center for the Treatment of Disease, Affiliated Hospital of Changchun University of Chinese Medicine, Changchun 130021, China | | | SHI Yuqing | School of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130117, China | | | ZENG Xueyuan | School of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130117, China | | | XIONG Huazhong | Center for the Treatment of Disease, Affiliated Hospital of Changchun University of Chinese Medicine, Changchun 130021, China | | | CHENG Zhifang | Department of Traditional Chinese Medicine, Changchun Hongqi First Community Health Service Center, Changchun 130021, China | | | REN Jixiang | Center for the Treatment of Disease, Affiliated Hospital of Changchun University of Chinese Medicine, Changchun 130021, China | renjx2003@163.com。 |
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| Abstract
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| [Objective] To analyze the 10-year risk of cardiovascular and cerebrovascular disease and traditional Chinese medicine（TCM） symptoms in 969 patients with metabolic syndrome，and to summarize the characteristics of changes in symptoms during the process of elevated disease risk. [Methods] The physical examination data and the TCM Four Diagnostic Information Scale were collected from September 2021 to January 2022 from patients with health checkups at the Affiliated Hospital of Changchun University of Chinese Medicine. The China-PAR model was used to assess the 10-year risk of cardiovascular and cerebrovascular disease in patients，and the hidden structure was used to summarize the TCM symptoms within three stroke risk levels. [Results] The number and proportion of 969 patients aged 40~60 years with metabolic syndrome at low，intermediate，and high risk of 10-year stroke were 411（42.41%），274（28.28%） and 284（29.31%） cases，respectively. A total of 42 TCM symptoms were included，and 8，14 and 9 hidden categories were obtained by stratifying the hidden structure model. Combined with the expert consultation，the respective symptoms of the three risk levels were obtained，and the low-risk patients mainly presented with spleen-kidney qi deficiency with dampness evidence and kidney-yin deficiency evidence；the medium-risk patients were characterized by heart-spleen deficiency with phlegm and liver-fire incandescence evidence，and the high-risk patients mostly presented with spleen-kidney deficiency evidence and liver-yang hyperactivity evidence. [Conclusion] Patients with metabolic syndrome are mostly at medium and high risk degree of cardiovascular disease at 10 years. Deficiency evidence is the basis for the transformation of patients with metabolic syndrome into cardiovascular and cerebrovascular disease risk，yin deficiency and yang hyperactivity are important manifestations for reaching the high-risk stage. |
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