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| Observation on the curative effect of Jiedu Xiaoyong Decoction in the period of hot toxin after operation of perianal necrotizing fasciitis |
| Hits 441 Download times 382 Received:March 18, 2023 |
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| DOI
10.11656/j.issn.1672-1519.2023.08.04 |
| Key Words
perianal necrotizing fasciitis;Jiedu Xiaoyong Decoction;traditional Chinese medicine treatment;the period of heat-toxin exuberance |
| Author Name | Affiliation | E-mail | | SUN Lida | Graduate School of Hebei University of Traditional Chinese Medicine, Shijiazhuang 050000, China | | | XING Wenyu | Graduate School of Hebei University of Traditional Chinese Medicine, Shijiazhuang 050000, China | | | WANG Qiushuang | Graduate School of Hebei University of Traditional Chinese Medicine, Shijiazhuang 050000, China | | | LI Boyan | Graduate School of Hebei University of Traditional Chinese Medicine, Shijiazhuang 050000, China | | | SHEN Ruihong | Graduate School of Hebei University of Traditional Chinese Medicine, Shijiazhuang 050000, China | | | WANG Jiaxin | Graduate School of Hebei University of Traditional Chinese Medicine, Shijiazhuang 050000, China | | | CHEN Xueqing | Anorectal Three Dermatology, First Affiliated Hospital of Hebei University of Traditional Chinese Medicine, Shijiazhuang 050000, China | cxqdjd@126.com |
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| Abstract
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| [Objective] To explore the clinical effect of Jiedu Xiaoyong Decoction in treating perianal necrotizing fasciitis with the period of heat-toxin exuberance after operation. [Methods] The 60 patients with perianal necrotizing fasciitis were randomly divided into observation group and control group,with 30 cases in each group. The control group was treated with postoperative symptomatic support routine treatment+Tong Yangxiao Lotion sitz bath,and the observation group was on the basis of the control group,and took the Jiedu Xiaoyong Decoction after the operation. [Results] VAS scores in the observation group were lower than those in the control group at day 3,7 and 14 after treatment,and the difference was statistically significant(P<0.05);After 14 days of treatment,white blood cells(WBC),C-reactive protein(CRP) and interleukin-6(IL-6) in both groups were significantly lower than before treatment,and the observation group was significantly lower than the control group(P<0.05),while hemoglobin(Hb) was significantly higher than before treatment,and the observation group was better than the control group(P<0.05);After 14 days of treatment,laboratory risk index score(LRINEC) and fournier gangrene severity index(FGSI) of necrotizing fasciitis in both groups were significantly lower than before treatment,and observation group was significantly lower than control group(P<0.05). The wound drainage and wound edema scores of the observation group were lower than those of the control group on the 7th and 14th day after treatment,and the difference was statistically significant(P<0.05). The wound healing time of observation group was shorter than that of control group(P<0.05). The total effective rate of observation group was better than control group(P<0.05). [Conclusion] The application of Jiedu Xiaoyong Decoction in the heat toxic peak period after the operation of perianal necrotizing fasciitis has definite curative effect,which can effectively relieve postoperative pain,reduce inflammatory response,improve hemoglobin content,facilitate the evaluation of postoperative condition and prognosis of patients,reduce postoperative wound seepage and wound edema,and accelerate wound healing. |
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