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| Analysis of the risk factors of depression and anxiety in COVID-19 patients in Tianjin based on traditional Chinese medicine syndrome elements |
| Hits 460 Download times 386 Received:May 18, 2023 |
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| DOI
10.11656/j.issn.1672-1519.2023.09.01 |
| Key Words
COVID-19;traditional Chinese medicine syndrome element;generalized anxiety;depression;risk factor |
| Author Name | Affiliation | | LIU Min | First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300193, China | | WANG Mutian | First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300193, China
Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | ZHAO Qiliang | First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300193, China | | ZHANG Dong | Tianjin Haihe Hospital, Tianjin 300350, China | | FAN Shuang | Tianjin Haihe Hospital, Tianjin 300350, China | | ZHANG Huiqi | First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300193, China |
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| Abstract
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| [Objective] To explore the impact of traditional Chinese medicine syndrome element distribution on concomitant anxiety/depression in corona virnus disease 2019（COVID-19） patients in Tianjin area. [Methods] The 176 locally confirmed COVID-19 cases admitted to Haihe Hospital in Tianjin from January 2020 to July 2020 were collected. Clinical data at admission were collected，and psychological questionnaires（GAD7，PHQ9） were conducted to calculate traditional Chinese medicine syndrome elements. Logistic regression analysis was used to analyze the impact of traditional Chinese medicine syndrome elements on concomitant anxiety/depression. [Results] The 176 patients with COVID-19 were included，including 102 patients with concomitant depression，112 patients with concomitant anxiety，and 99 patients with concomitant depression and anxiety. The 20 types of traditional Chinese medicine syndrome elements（9 types of disease location syndrome elements and 11 types of disease nature syndrome elements） were calculated. Univariate analysis showed that the disease was located in the spleen and liver，with a high proportion of qi stagnation and concomitant depression；the disease is located in the spleen and liver，characterized by heat，phlegm，qi stagnation and food accumulation，with a high proportion of accompanying anxiety；Logistic multiple factor regression analysis showed that the location of the disease in the liver（OR=10.346） and the nature of the disease as qi stagnation（OR=1.152） were risk factors for concomitant depression；the location of the disease in the spleen（OR=3.380），liver（OR=9.791），and fever（OR=4.358） are risk factors for individuals with anxiety state；the location of the disease in the spleen（OR=2.259），liver（OR=12.057），and qi stagnation（OR=2.731） are risk factors for individuals with depression and anxiety. [Conclusion] Among COVID-19 patients in Tianjin，the presence of liver or qi stagnation increases the risk of accompanying depression. The presence of liver or spleen or heat increases the risk of accompanying anxiety. The presence of liver or spleen or qi stagnation increases the risk of accompanying depression and anxiety. |
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