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| Research on risk factors and correlation of Chinese medical evidence features in patients on maintenance haemodialysis with restless legs syndrome |
| Hits 356 Download times 240 Received:June 08, 2023 |
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| DOI
10.11656/j.issn.1672-1519.2023.09.04 |
| Key Words
restless legs syndrome;maintenance hemodialysis;traditional Chinese medicine syndrome elements;risk factor |
| Author Name | Affiliation | | YIN Sujuan | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | HAN Yingying | Department of Nephrology, Tianjin First Central Hospital, Tianjin 300192, China | | CHANG Wenxiu | Department of Nephrology, Tianjin First Central Hospital, Tianjin 300192, China |
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| Abstract
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| [Objective] To investigate the risk factors and traditional Chinese medicine（TCM） evidence features of maintenance haemodialysis（MHD） patients with complications of restless legs syndrome（RLS）. [Methods] From September 2021 to October 2022，the 305 patients with MHD treated at the blood purification center of Tianjin First Central Hospital were selected and divided into positive and negative groups according to the occurrence of restless legs syndrome，including 72 patients in the RLS positive group and 233 patients in the RLS negative group. The risk factors of patients with MHD complicated with RLS and the relationship with the characteristics of Chinese medical evidence were analyzed by Logistic regression. [Results] Multi-factor Logistic regression analysis showed that Hb＜110 g/L，PTH≥350 pg/mL，and primary diabetic nephropathy were risk factors for complications of RLS in patients with MHD（P＜0.05）. The most common pathogenic evidence elements were blood deficiency 45（62.50%），yin deficiency 42（58.33%），dampness 40（55.56%） and moving wind 38（52.78%），while the most common pathogenic evidence elements were kidney 50（69.44%），liver 44（61.11%），meridian 41（56.94%） and spleen 36（50.00%）. In the regression analysis of evidence elements and risk factors，age was a risk factor for blood deficiency，dampness and phlegm，and primary glomerular disease was a risk factor for qi deficiency and blood stasis. [Conclusion] Diabetic nephropathy，anemia，and high PTH levels were independent risk factors for MHD complicated by RLS. MHD complicated RLS is complicated by common elements of TCM such as kidney，blood deficiency，liver，and yin deficiency，and the age is positively correlated with blood deficiency，dampness，and phlegm syndrome，and chronic glomerulonephritis is positively correlated with qi deficiency and blood stasis. |
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