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| Research progress on the mechanism of traditional Chinese medicine in the treatment of chronic obstructive pulmonary disease |
| Hits 544 Download times 481 Received:April 15, 2023 |
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| DOI
10.11656/j.issn.1672-1519.2023.09.19 |
| Key Words
chronic obstructive pulmonary disease;pathogenesis;traditional Chinese medicine |
| Author Name | Affiliation | E-mail | | JIA Bei | Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique of Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | HE Jiachen | Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique of Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | LI Jiawei | Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique of Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | LIU Zhidong | Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique of Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | liuzhidong@tjutcm.edu.cn |
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| Abstract
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| Chronic obstructive pulmonary disease（COPD） is a common disease with persistent airflow limitation as a clinical feature，manifested by chronic bronchitis，parenchymal lung lesions，emphysema，inflammation，airway remodeling，and other pathological features. Among its high prevalence，disability，and mortality rates，it is one of the leading causes of death worldwide. Medication is often used to treat COPD，such as glucocorticoids or bronchodilators，which are prone to drug resistance and have more adverse effects（rash，tachycardia，dizziness，metabolic disorders，mental disorders，etc.）. Traditional Chinese medicine improves lung function with clinical symptoms in COPD patients and reduces exacerbation or recurrence of COPD disease. There is promising research on its use in the treatment of COPD. This paper investigates the pathogenesis of slow obstructive pulmonary disease and the mechanism of Chinese herbal medicine for the treatment of slow obstructive pulmonary disease. It is significant for the further exploration of the activity and safety of Chinese herbal resources as therapeutic drugs for chronic obstructive pulmonary disease. |
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