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| Clinical observation on the adjuvant treatment of acute pancreatitis with Fu excess heat syndrome with modified Jinhuang ointment |
| Hits 335 Download times 276 Received:July 10, 2023 |
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| DOI
10.11656/j.issn.1672-1519.2023.10.04 |
| Key Words
acute pancreatitis;modified Jinhuang ointment;Chinese medicine syndrome scores;pain;inflammatory cytokines |
| Author Name | Affiliation | | YU Chunying | Department of Spleen, Stomach and Liver Diseases, Cangzhou Hospital of Traditional Chinese and Western Medicine of Hebei Province, Cangzhou 061000, China | | LI Li | Department of Spleen, Stomach and Liver Diseases, Cangzhou Hospital of Traditional Chinese and Western Medicine of Hebei Province, Cangzhou 061000, China | | CHEN Wei | Department of Spleen, Stomach and Liver Diseases, Cangzhou Hospital of Traditional Chinese and Western Medicine of Hebei Province, Cangzhou 061000, China |
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| Abstract
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| [Objective] To explore the effect of acute pancreatitis（AP） with Fu excess heat syndrome with modified Jinhuang ointment. [Methods] Sixty patients with AP with fu excess heat syndrome admitted to our hospital from October 2021 to October 2022 were selected and divided into control group（30 case） and study group（30 case） according to the random number table method. The control group received conventional western medicine treatment，while the research group received modified Jinhuang ointment external application on the basis of the control group. Compare the traditional Chinese medicine syndrome scores，visual analogue scale（VAS） scores and inflammatory cytokines [C-reactive protein（CRP），interleukin（IL）-6，IL-1β and tumor necrosis factor-α（TNF-α）] level between the two groups before and after treatment，calculate the recovery time of gastrointestinal function，clinical efficacy，and incidence of adverse reactions. [Results] After treatment，the total effective rate of the study group was 96.67%，which was higher than 80.00% of the control group（P＜0.05）. The main symptoms，secondary symptoms，and total scores of traditional Chinese medicine syndromes in the research group were lower than those in the control group（P＜0.05）. The level of CRP，IL-6，IL-1β，TNF-α and VAS score in the research group were lower than those in the control group（P＜0.05）. The recovery time of abdominal distension，bowel sounds，eating and defecation in the study group was shorter than that in the control group（P＜0.05）. There was no statistically significant difference in the incidence of adverse reactions between the two groups（P＞0.05）. [Conclusions] The combined use of modified Jinhuang ointment in routine treatment for AP patients can effectively alleviate their clinical symptoms，alleviate pain levels，inflammatory reactions，promote gastrointestinal function recovery，improve efficacy，and have fewer adverse reactions. |
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