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| Study on traditional Chinese medicine syndrome regularity of HR-HPV infection and cervical lesions |
| Hits 540 Download times 340 Received:April 15, 2023 |
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| DOI
10.11656/j.issn.1672-1519.2023.10.05 |
| Key Words
HR-HPV infection;cervical lesion;traditional Chinese medicine syndrome regularity |
| Author Name | Affiliation | | XU Xintong | Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | GUO Jie | Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China | | SONG Dianrong | Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China | | ZHAO Lin | Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China | | CHEN Xiujie | Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China | | LU Di | Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China |
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| Abstract
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| [Objective] To study the evolution of traditional Chinese medicine（TCM） syndromes in patients with HR-HPV infection and cervical lesions，and provide evidence support for TCM treatment of HPV infection and cervical lesions. [Methods] 943 patients with HR-HPV infection and colposcopy were included in the gynecological clinic of the Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine from September 2020 to August 2022. The information of the four diagnostic methods of traditional Chinese medicine was collected. According to the pathological results after colposcopy，they were divided into HPV infection group，LSIL group and HSIL group. TCM syndrome characteristics of each group were analyzed and compared. [Results] The main location of HR-HPV infection and cervical lesions was the uterus（76.78%），followed by liver（75.19%），kidney（42.52%） and spleen（25.45%）；The main pathogenic factor was dampness（72.85%），followed by qi stagnation（69.46%），yin deficiency（65.32%），blood stasis（59.60%） and yang deficiency（52.92%）. The results of cluster analysis showed that the TCM syndromes of HPV infection group were dampness stagnation in the uterus，liver depression and qi stagnation，yin deficiency and fire hyperactivity，kidney-yang and qi deficiency，and heart and spleen deficiency. In LSIL group，there were damp-heat syndrome in the uterus，liver depression and qi stagnation syndrome，kidney yang and qi deficiency syndrome；HSIL group was divided into damp-heat down-injection syndrome，liver-qi stagnation syndrome，spleen and kidney deficiency syndrome. [Conclusion] HR-HPV infection and cervical lesions are mostly caused by dampness，which can be treated with reference to the illness bellow the belt. The core area of this disease is located in the uterus. It is complicated with multiple viscera of liver，spleen and kidney. The pathogenic factors are mainly dampness and evil，presenting the pathological characteristics of deficiency and excess mixed，and positive deficiency and evil excess. Emotional illness is an important feature of this disease. |
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