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| Research progress on the mechanism of traditional Chinese medicine against depression |
| Hits 561 Download times 852 Received:June 25, 2023 |
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| DOI
10.11656/j.issn.1672-1519.2023.10.19 |
| Key Words
traditional Chinese medicine;depression;antidepressant;mechanism;research progress |
| Author Name | Affiliation | | GAO Ce | Graduate School, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China | | HU Xiamin | Graduate School, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
College of Pharmacy, Shanghai University of Medicine & Health Sciences, Shanghai 201318, China |
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| Abstract
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| Depression is a kind of mental disorder which seriously endangers human health. And it belongs to the category of “depression syndrome” in traditional Chinese medicine（TCM），and its pathogenesis is complex. At present，antidepressants generally have the characteristics of low effective rate，high addiction and serious adverse reactions，while TCM is particularly significant in the treatment of depression because of its multi-targets，multi-pathways and overall dialectical effects. Based on the antidepressant literature of TCM published in the past 5 years，this paper summarizes the antidepressant TCM through a variety of mechanisms，and puts forward new mechanism ideas on the basis of previous studies. In order to provide clinical application basis and new research direction for the treatment of depression with TCM. |
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