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Cross sectional investigation on traditional Chinese medicine syndrome of 9472 confirmed cases of children with influenza in China from 2019 to 2020
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DOI   10.11656/j.issn.1672-1519.2023.12.01
Key Words   children;influenza;traditional Chinese medicine syndrome
Author NameAffiliationE-mail
ZHANG Xilian First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China 
 
MA Rong First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China 
mr1974@163.com 
WANG Hongwu School of Public Health, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
RONG Ping First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China 
 
WANG Mengyang School of Public Health, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
WANG Chengting Tianjin Children's Hospital, Tianjin 300074, China  
AN Zimeng First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China 
 
CHEN Zhaoyuan First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China 
 
Abstract
    [Objective] Since there is currently no standardized traditional Chinese medicine(TCM) classification of influenza in children,the purpose of this study is to investigate the distribution of traditional Chinese medicine syndromes of childhood influenza in winter and spring of 2019-2020,and to provide reference for accurate clinical diagnosis and treatment. [Methods] Based on the literature study and expert questionnaires of Delphi method,we developed the “Children's Influenza Chinese Medicine Syndrome Questionnaire” and used a cross-sectional survey method of stratified simple random sampling to conduct a questionnaire survey in 18 tertiary hospitals in 6 administrative regions of China. We analyzed and summarized the distribution characteristics of TCM syndromes in children of different ages,different influenza types and different regions,and the characteristics of symptoms in children of each type. [Results] Among 9 472 children,1) syndrome of wind heat invading health accounted for 46.63%,syndrome of exterior cold and interior heat 23.41%,toxic-heat internal trapping 11.07%,exterior cold syndrome 8.12%,syndrome of pathogen invading the lung and stomach 5.87%,syndrome of heat toxin invading the lung 4.88%,and syndrome of healthy qi deficiency and lingering pathogen 0.02%. 2) Ultra-high fever accounted for 4.30%,high fever 44.52%,moderate fever 44.37%,and low fever 6.79%. 3) Influenza A accounted for 90.51% and influenza B 9.49%,both of which were dominated by syndrome of wind heat invading health(46.44% and 48.50%,respectively). 4) At different stages of fever,syndrome of wind heat invading health and syndrome of exterior cold and interior heat were common,and the proportion of exterior cold syndrome gradually decreased and the proportion of syndrome of heat toxin invading the lung gradually increased as the fever duration progressed. 5) syndrome of wind heat invading health and syndrome of exterior cold and interior heat were prevalent in all age groups,and syndrome of wind heat invading health was predominant in all regional TCM syndrome.[Conclusion] Influenza A is the predominant type of influenza in Chinese children from 2019 to 2020,and syndrome of wind heat invading health and syndrome of exterior cold and interior heat are the predominant TCM syndromes,and other syndromes are dominated by moderate to high fever. The distribution of TCM syndromes among different ages,types and regions are dominated by syndrome of wind heat invading health.

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