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| Theoretical analysis on pathogenesis of internal toxin |
| Hits 653 Download times 400 Received:September 21, 2023 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1672-1519.2024.01.08 |
| Key Words
internal toxin;theoretical source and flow;etiology and pathogenesis;treatment principles and laws;research idea |
| Author Name | Affiliation | E-mail | | SU Wenquan | Second Ward Department of Brain Disease, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China | | | DU Yawei | National Drug Clinical Trial Institution, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China | | | WU Shengxian | Second Ward Department of Brain Disease, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China
National Drug Clinical Trial Institution, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China | wushx@sina.com |
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| Abstract
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| The theory of internal virulence originated from the theory of virulence in the Qin and Han Dynasties. In Jin,Sui,Tang and Song Dynasties,the types of internal toxin were refined and the theoretical connotation was enriched. In Ming and Qing Dynasties,a relatively complete theoretical system of endogenous virulence was formed. The etiology and pathogenesis of internal toxicity are summarized in yin and yang discrimination,and are closely related to internal and external,qi and blood,and zangfu organs. Internal and external pathogenic sources can be divided,but both of them take “depression” and internal toxicity as the core pathogenesis. Qi,blood and zangfu organs are not only the source of internal toxicity,but also the location of internal toxicity. With different levels of qi,blood and zangfu organs injured by internal poison,the symptoms and symptoms are different. The treatment of internal poison is to avoid evil,remove evil and detoxify,fuzheng supporting poison and regulating the shape of the mind. The methods of warding off evil and preventing disease include “avoiding external sensation” and “preventing endogenous poison”,among which the treatment of depression is the key to prevent endogenous poison,and its treatment is to regulate qi and blood,peace and zangfu organs. To remove evil and detoxify,we can adopt the method of “clearing poison inside and detoxifying outside”,and pay attention to the compatibility of sanjie drugs. Fuzheng supporting poison method in addition to supplementing positive qi,also need to pay attention to the situation,to homeopathic supporting poison out. Regulating the form and calming the spirit is to repair the shape and spirit corrupted by poison and evil,and can be combined with channeling drugs to direct the disease. Through the new theory of innovation breakthrough and the new method of combining Chinese and Western,it promotes the modern development of the theory of internal virulence. |
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