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Based on the function of mitochondria to explore the internal mechanism of zongqi theory in treating of chronic obstructive pulmonary disease
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DOI   10.11656/j.issn.1672-1519.2024.01.22
Key Words   chronic obstructive pulmonary disease;zongqi theory;peitu shengjin;mitochondria
Author NameAffiliationE-mail
WU Qingyuan Graduate College, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
GUO Sijia The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China 379541418@qq.com 
SUN Zengtao Department of Hospital Management, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
LI Xiaodan The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China  
Abstract
    Chronic obstructive pulmonary disease(COPD) is a common and frequently occurring disease of the respiratory system. Due to its high disability rate,it has a serious negative impact on the quality of life and socio-economic development of patients. Traditional Chinese medicine believes that “deficiency,phlegm,and blood stasis” are its core pathogenesis,and the rise and fall of zongqi runs through the entire evolution of its pathogenesis. The method of peitu shengjin is a representative treatment method for COPD based on the theory of zongqi,which has been widely used in clinical treatment of COPD. Modern medicine has confirmed that mitochondrial functional and morphological disorders are important biological mechanisms for the occurrence and development of COPD pathology and pathophysiology. This article starts from the internal relationship between “deficiency,phlegm,blood stasis” and mitochondrial function,and explores the role and mechanism of zongqi theory and the method of cultivating soil and generating gold in the treatment of COPD,in order to provide basis and guidance for its clinical application.

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