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Research progress and thinking of coronary heart disease animal model based on the combination of traditional Chinese medicine disease and syndrome
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DOI   10.11656/j.issn.1672-1519.2024.02.20
Key Words   coronary heart disease;animal model;combination of disease and syndrome;phlegm and blood stasis
Author NameAffiliationE-mail
DONG Yurong Clinical School of Thoracic, Tianjin Medical University, Tianjin 300070, China  
XIE Cun Emergency Department, Chest Hospital of Tianjin University, Tianjin 300222, China
Tianjin Key Laboratory of Cardiovascular Emergency and Critical Care, Tianjin Municipal Science and Technology Bureau, Tianjin 300222, China 
 
LIU Chang Clinical School of Thoracic, Tianjin Medical University, Tianjin 300070, China  
ZHAO Jia Emergency Department, Chest Hospital of Tianjin University, Tianjin 300222, China
Tianjin Key Laboratory of Cardiovascular Emergency and Critical Care, Tianjin Municipal Science and Technology Bureau, Tianjin 300222, China 
orange2012@126.com 
WANG Shuo Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301607, China
State Key Laboratory for Component-based Chinese Medicine, Tianjin University of Traditional Chinese, Tianjin 301617, China 
wssean1609@163.com 
Abstract
    Clinical research and animal experimental study of coronary heart disease(CHD) is always the focus in the cardiovascular field. The animal model of combination of disease and syndrome embodies the idea of integration of traditional Chinese medicine(TCM) and Western medicine. It not only has the disease characteristics of Western medicine,but also displays the unique TCM syndrome characteristics with the help of TCM thinking and different experimental methods,which is the effective tool to prevent and treat coronary heart disease by traditional Chinese medicine. In this paper,the methods of establishing animal models of TCM syndrome of CHD were summarized,and we taken the animal models of CHD with phlegm-blood stasis syndrome as an example and put forward our points.

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